Search
Now showing items 1-10 of 103
Studies on production and function of pulmonary nitric oxide
(1999-05-14)
Nitric oxide is involved in pulmonary vascular and bronchial regulation
and appears to be of paramount importance in the adaptation of the
pulmonary circulation at birth. Nitric oxide is present in exhaled gas.
The main ...
Humoral and cellular immune responses to proteins encoded by the hepatitis C virus
(1997-11-17)
. Little is known about the basic immunogenicity and antigenicity of HCV proteins. Therefore, the immunogenicity and antigenicity of the HCV NS3 protein were characterized in mice. All tested haplotypes were antibody responders to NS3.
The finding...
The diagnosis and protection of the auditory peripheral system
(1999-01-15)
would be temporary.
The second part of the thesis was focused on finding a means of protecting against hearing loss. By infusing the cochlea with the neurotrophic factor, NT-3, we found that aminoglycoside-induced degeneration of the spiral ganglion...
On the mechanisms of action of atypical antipsychotic drugs : an experimental study
(1999-05-28)
liability, respectively. Systemic administration of clozapine or risperidone as well as amperozide markedly enhanced DA efflux. in the medial prefrontal cortex (mPFC), an effect that was not mimicked by the D2/3 or 5-HT2A/C receptor antagonists raclopride...
Allergen-induced late airways reaction in the pig : influence of endogenous and exogenous glucocorticoids
(1995-11-24)
obstruction starting 3.5-4 h after allergen challenge was seen in pigs treated with the cortisol-synthesis inhibitor metyrapone, but not in pigs with high cortisol levels obtained in response to stress due to anaesthesia and surgical manipulation.
Bloodflow...
Exercise effects on the mitogen-activated protein (MAP) kinase cascade in skeletal muscle
(2000-11-03)
was assessed. ERK1/2 and p38 MAP kinase phosphorylation was increased 1.6- and 2.3-fold, respectively by contractions, with no change in ERK1/2 and p38 MAP kinase protein expression. ERK1/2 displayed a fiber-type specific pattern of protein expression...
Role of corticotropin-releasing factor, somatostatin and leptin in vagal nerve function and control of gastric emptying
(1998-11-13)
suggest that LR are present in cholinergic neurones of the DMX Injection of leptin (0.013-3.9 µg) 4th i.c.v. suppressed gastric emptying of glucose during fill, but did not affect postprandial emptying. The suppression of emptying during fill was abolished...
Afferent input to midbrain dopamine neurones and its modulation : an electrophysiological study i vitro
(1999-09-24)
glutamatergic and GABAergic synaptic transmission to the DA neurones. These effects were completely blocked by the M3/M1 receptor antagonist 4-DAMP, but not significantly affected by the M, receptor antagonist pirenzepine. Moreover, the postsynaptic responses...
Studies on acupuncture treatment of xerostomia
(1999-09-24)
sensitivity (0.89) and a good positive predictive value (0.74) in identifying patients who may respond to acupuncture treatment of xerostomia.
The fifth study was a retrospective investigation, determining the long-term effects up to 3 years of acupuncture...
Nerve growth factor : its contribution to neuroimmunomodulation
(1999-11-26)
Nerve growth factor (NGF) is the best characterised member of the neurotrophin family, a protein group with common structures and functions. Similar to other proteins of neuronal origin NGF, in addition to its well described ...