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The effects of haemodialysis and metabolic acidosis on protein metabolism
(2000-11-24)
haemodialysis, the total concentration and the proportion of polyribosomes decreased by 29 ± 6% and 8 ± 4% (mean ± SEM, p<0.05), respectively, in the patients and by 22 ± 5% and 7 ± 2 % (p<0.01) in the healthy subjects. With the flooding-dose technique...
Factors associated with brain tumor risk : with focus on female sex hormones and allergic conditions
(2008-09-03)
Every year approximately 1200 people in Sweden are diagnosed with a brain
tumor. The two main histological types of brain tumors, gliomas and
meningiomas, differ in terms of their localization, histology, prognosis,
and ...
Oncologic and functional outcomes after robot-assisted radical hysterectomy for cervical cancer
(2020-10-16)
Background: Cervical cancer is the fourth most common cancer in women worldwide, but the incidence has rapidly declined in developed countries after the introduction of structured screening programs. This disease is caused ...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
Background: Atherosclerosis is a modern world scourge and the number of people worldwide diagnosed with type 2 diabetes (T2D) is on the rise, causing much morbidity and mortality. Endothelial dysfunction (ED) is an early ...
Complications following anterior cruciate ligament reconstruction
(2021-02-16)
Background: Venous thromboembolism (VTE) and septic arthritis (SA) are two rare complications following anterior cruciate ligament reconstruction (ACLR). Due to their rare incidence, risk factors and outcome are difficult ...
Depression in youth and adults : etiology, outcomes, and comorbidities
(2022-02-02)
Depression is a common and debilitating mental disorder characterized by low mood, loss of interest in activities, and long-lasting functional impairment. It is a worldwide psychiatric illness with a wide range of ages of ...
Elevated fasting glucose levels in obese children and adolescents : prevalence and long-term consequences
(2016-01-29)
Background: Obesity in childhood and adolescents is a major concern in Sweden, as in many parts of the world. Already during the pediatric years is obesity associated with several metabolic complications, which often ...
Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight
(2018-08-17)
to follow up consequences of prematurity or low birth weight at term compared to term controls with normal birth weight in two different cohorts. The first cohort of children, studied at a mean age of 9.7 and again at 12.6 years (studies I-III), were born...
Biological therapy in rheumatoid arthritis : epidemiological studies
(2014-05-09)
The landscape of RA treatment has unquestionably changed dramatically during the last decade. A deeper understanding of the pathophysiological and immunological mechanisms in RA, earlier and more aggressive treatment, and ...
Multiple circuits controlling the versatility of locomotion : molecular and connectivity principles in zebrafish
(2022-11-24)
Locomotion is produced by neuronal circuits in the spinal cord. These motor circuits rely on the activation of supraspinal centres and transform descending excitatory drive into coordinated rhythmic activity. Far from ...