Search
Now showing items 1-8 of 8
Immune responses to the Ro and La autoantigens
(1999-05-07)
Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE) are rheumatic diseases characterized by autoantibody production directed to the Ro/SS-A and La/SS-B autoantigens. The Ro/SS-A is a complex of one of four small ...
Meiotic chromosome segregation : molecular analysis of the synaptonemal complex
(2000-03-24)
Meiosis is a special type of cell division that produces haploid gametes from diploid parental cells. As such, meiosis stands at the gateway to sexual reproduction in most eukaryotic organisms. During meiosis, a complex, ...
The effects of hand training in patients with Welander distal myopathy and myotonic dystrophy type 1
(2009-05-19)
The overall aim was to study and gain knowledge about the effects of hand
training on both functional capacity such as hand function and Activities
of Daily Living (ADL) in patients with Welander distal myopathy (WDM) ...
Genotype-phenotype relations in SF3B1 mutated myelodysplastic syndromes with ring sideroblasts
(2016-10-28)
Myelodysplastic syndrome with ring sideroblasts (MDS-RS) is a clonal hematopoietic stem cell disorder characterized by hyperplastic and ineffective erythropoiesis, ring sideroblasts in the bone marrow, and anemia. Heterozygous ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Roles of Myc and Mad in cell cycle and apoptosis
(2006-05-12)
induced by etoposide, doxorubicin, and cisplatin. Furthermore, we found that etoposide and doxorubicin signaling involved activation of pro-apoptotic Bax and of caspase 3 and 9. In addition, etoposide required proapoptotic PKCdelta for efficient apoptosis...
Register-based studies of sex steroid hormones and psychiatric disorders
(2023-01-27)
The focus of this thesis is the interplay between sex steroid hormones, psychiatric- and
neurodevelopmental disorders and adverse behavioral outcomes. Sex steroid hormones
are mostly known for their role in sexual ...
Neuroblastoma as a target for effector mechanisms of the immune system
(2007-05-24)
Neuroblastoma (NB) is the most common solid extracranial tumor in
children. Despite intensive multimodal treatment, the prognosis for
high-risk NB patients remains poor and therefore new treatment modalities
are needed. ...