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Folding and retention of rotavirus glycoproteins in the endoplasmic reticulum
(2000-05-19)
with calnexin, a lectin-like chaperone, during oligosaccharide processing. This interaction was found to be glycan- and time-dependent. Novel experiments with castanospermine, a glucosidase 1 and II inhibitor, revealed that glucose trimming and calnexin NSP4...
Unstable post-infarction ischemia : identification and risk stratification with special emphasis on noninvasive methods
(1996-03-22)
Although in-hospital mortality after acute myocardial infarction has decreased, long-term mortality is still high. This study tested the prognostic value of detecting residual myocardial ischemia by different techniques ...
Minskar medial knäsmärta med ökad höftmuskelstyrka? En litteraturstudie
(2013-10-11)
Background: The knee joint is a common source of pain and the most common localization of this pain is the medial part of the humero-tibial joint. Pain can induce a change in the recruitment of muscles, there may be a ...
Small molecules as research tools for studying the biology of the tumour suppressor p53
(2011-05-24)
p53 is a potent tumour suppressor that is inactivated in the majority, if not all human
cancers. In about 50% of the cases, the gene is mutated and in the rest it is rendered
inactive mainly by deregulation of its ...
Epidemiology, risk and protective factors of self-immolation : a study from Iran
(2013-04-04)
Background: Suicide by self-burning (self-immolation) is one of the suicide methods that is far more common in low-middle income countries than in high-income ones. Iran is one of the countries that has a high rate of ...
Studies of stem cell and adhesion proteins in breast cancer
(2014-10-06)
characterized by relatively low levels of ESR1 (ERα) as compared to cluster alpha. Clustering analysis performed on clinical samples also generated two distinct groups with low ESR1 levels. Further analysis of these three clusters will show whether...
Genetic regulation of neuroinflammation after infection and injury
(2012-05-16)
at two different stages of neurotropic HSV-1 virus CNS entry. Thus, the calcitonin receptor (Calcr) gene was identified as a candidate for peripheral neuronal infection and propagation to the CNS, while the von Willebrand factor (Vwf) gene was identified...
Long-term consequences of preterm birth : Swedish national cohort studies
(2011-05-06)
The World Health Organization defines preterm birth as birth before 37 complete weeks. The proportion of very preterm children with severe neurological disabilities has become smaller, but bulks of data indicate that, for ...
Clinical studies on drug treatment of hospitalised patients : general infectious diseases and acute myocardial infarction
(2013-05-03)
Treatment of hospitalised patients is generally governed by the pre-developed algorithms and common guidelines. These approaches are helpful in most, but not all cases. Treatment of hospitalised patients is limited to the ...
Exploring the therapeutic effects of p53 modulation in cancer and immune cell biology
(2023-04-26)
found that spatial cross-presentation within tumors correlated with increased overall survival, independently of tumor grade or expression of regulatory functions, such as Foxp3 and CD274, encoding PD-L1. Hence, our data suggests that intra...