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Hyperlipidaemia : an evaluation of management and attitudes among doctors and knowledge and attitudes in the population
(1999-09-10)
An evaluation of management and attitudes among doctors and knowledge and attitudes in the population Coronary heart disease (CHD) is the main cause of death in the western world, and hyperlipidaemia is one of the major ...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
Background: Atherosclerosis is a modern world scourge and the number of people worldwide diagnosed with type 2 diabetes (T2D) is on the rise, causing much morbidity and mortality. Endothelial dysfunction (ED) is an early ...
Do you see my pain? Aspects of pain assessment in hospitalized preverbal children
(2018-05-02)
Background and aim: Pain in hospitalized preverbal children is underassessed and undermanaged. According to the Social Communication Model of Pain, pain is both a personal experience and a social construction, influenced ...
Genotype-phenotype relations in SF3B1 mutated myelodysplastic syndromes with ring sideroblasts
(2016-10-28)
Myelodysplastic syndrome with ring sideroblasts (MDS-RS) is a clonal hematopoietic stem cell disorder characterized by hyperplastic and ineffective erythropoiesis, ring sideroblasts in the bone marrow, and anemia. Heterozygous ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Epidemiological aspects of sarcoidosis : risk factors and long-term consequences
(2021-01-27)
predictors in sarcoidosis. We found a 2.4-fold increased relative risk of heart failure associated with sarcoidosis that was higher during the first two years since sarcoidosis diagnosis and in individuals without a history of ischemic heart disease. Diabetes...
Too much, too late? Drug prescribing for older people near the end of life
(2019-08-28)
% CI 1.1 to 1.9), antiplatelet agents (- 1.5%, 95% CI -1.8 to -1.2), statins (-4.7%, 95% CI -5.0 to -4.4), bisphosphonates (-0.3%, 95% CI -0.4 to -0.2), or vitamins (+1.0, 95% CI 0.8 to 1.2). During the last year before death, median drug costs amounted...
The role of proprotein convertases in vascular disease
(2022-10-18)
+ T cells. Microarray analysis of spleens confirmed that expression of T cell markers Cd4, Cd3e and Cd3g was upregulated in Pcks6-/- mice vs. controls. In vitro, splenocytes isolated from Pcks6-/- mice secreted higher levels of IFN-g, IL-2, IL-17 and IL-10...