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Alcohol, sickness absence and disability pension : a study in the field of disease, ill health, psychosocial factors, and medicalisation
(1999-08-13)
In Sweden 1998 there were 34 487 newly granted DPs (disability pensions) irrespective of diagnosis and 466 (1.4 %) with a main diagnosis of alcohol dependence or abuse. Other studies have shown that alcohol diagnoses are ...
Regulation of gene expression by non-protein-coding RNAs
(2009-01-29)
The human genome sequencing projects revealed that the human genome contains over 3 billion DNA base pairs, but only 20,000 25,000 protein-coding genes. In fact, only about 1.2% of the genome codes for proteins. Surprisingly, ...
Obesity, life style and society : psychological and psychosocial factors in relation to body weight and body weight changes
(2004-04-16)
This dissertation consists of two cross-sectional population studies
(studies I and IV), and two prospective studies (studies II and III).
In study I the relative importance of obesity for self-rated health with
focus ...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Immunoregulatory effects of placenta-derived decidual stromal cells
(2016-01-08)
Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated ...
Oxidoreductases and RNA degradosome controlling virulence-associated traits of Salmonella enterica serovar Typhimurium
(2013-09-04)
The oxidative stress response is a fundamental and primitive mode of innate immune defense in nearly all forms of life. The host oxidative stress response becomes truly important and effective especially against intracellular ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
BACKGROUND AND AIMS: Obstetric anal sphincter injury (OASIS) may cause anal incontinence, as well as sexual dysfunction and psychological trauma. Mediolateral and lateral episiotomy have been shown to be protective against ...
Persistent inflammatory pathways in rheumatoid arthritis despite anti-rheumatic treatment
(2010-11-18)
The past years have witnessed tremendous progress in the treatment of rheumatoid arthritis, a chronic debilitating autoimmune disease mainly characterized by joint inflammation with progressive tissue destruction and loss ...