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Life course determinants of women’s health : from reproductive age to menopause
(2021-04-26)
Over the past four decades, growing evidence has indicated that characteristics such as birth weight and length of gestation are not only key indicators for infant’s health, but also predictors of adult health and disease ...
The effect of alpha-HGA on HIV-1 replication
(2009-03-13)
the mechanism of [14C]alphaHGA uptake by human T cell line. Uptake of [14C]alphaHGA into H9 cells was time- and dose- dependent. The uptake properties showed low temperature dependency (Q10<2) and the cellular uptake of [14C] labeled alphaHGA was not inhibited...
Significance of adipose tissue characteristics for development of metabolic complications in obesity
(2014-11-14)
Background: Obesity is closely related to development of insulin resistance and dyslipidemia. Intrinsic properties of adipose tissue are also of great importance for obesity related comorbidity. The aim of this thesis was ...
Paracrine regulation of Sertoli cell proliferation
(2003-02-14)
the effects of growth factors and cytokines, thought to be of physiological or pathophysiological relevance. Sertoli cells from 8 to 9-day-old rats were isolated and cultured under scrum-free conditions. Proliferation was assessed by three different methods; 3...
Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight
(2018-08-17)
to follow up consequences of prematurity or low birth weight at term compared to term controls with normal birth weight in two different cohorts. The first cohort of children, studied at a mean age of 9.7 and again at 12.6 years (studies I-III), were born...
Physical workload in surgery : from risk assessments to interventions
(2022-05-20)
Surgeons often suffer from work-related musculoskeletal disorders (WMSDs), with the neck, shoulders, and low back being the most affected body sites. Among other factors, the high physical workload has been recognized as ...
Epidemiological and clinical aspects of fertility and diseases associated with infertility among Swedish-born and foreign-born women
(2007-05-18)
Objective: To examine the association between sociodemographic factors and first birth country of birth and hospitalization for pelvic inflammatory disease (PID), ectopic pregnancy (EP), infertility trends in Sweden during ...
The role of SOXC transcription factors in B-cell development and lymphoid malignancies
(2017-09-15)
Mantle cell lymphoma (MCL) accounts for 5-10% out of all Non-Hodgkin lymphomas (NHLs) and is one of the most aggressive forms of lymphomas with a median survival of less than 5 years. Currently, MCL is considered to be an ...
Cardioplegia and cardiac function : evaluated by left ventricular pressure-volume relations
(2000-05-26)
Purpose: This thesis is focused on studies of blood cardioplegia in order to evaluate regimens of myocardial protection during cardiac surgery. To further bring down operative mortality and morbidity, in patients with ...
The development of psychiatric disorders and adverse behaviors : from context to prediction
(2022-01-28)
Psychiatric disorders by definition cause significant impairment in an individual’s daily functioning. Certain disorders, such as borderline personality disorder (BPD) and eating disorders, have worse prognosis and high ...