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Taeniasis and cysticercosis in Honduras : epidemiological, serological, and clinical aspects
(1999-01-15)
Taenia solium taeniasis and cysticercosis are recognised as important and increasing public health problems in Latin America. These infections not only have a significant socio-economical impact due to chronic morbidity, ...
Asthma during pregnancy in a population-based study : pregnancy complications and adverse perinatal outcomes
(2017-01-02)
BACKGROUND: Asthma is one of the most common chronic diseases, and prevalence,
severity and medication may have an effect on pregnancy. We examined maternal
asthma, asthma severity and control in relation to ...
Non-linear synaptic integration on dendrites of striatal medium-spiny neuron : a computational study
(2016-11-25)
Striatum is the main input nucleus of basal ganglia. Medium-spiny neurons (MSNs), the principal neurons of the striatum, receive convergent excitatory inputs from cortex and thalamus, thus “gate” the information flow to ...
Elucidating regulatory elements : studies in chronic lymphocytic leukemia and multiple myeloma
(2018-12-21)
With next generation sequencing taking center stage in genetic and epigenetic research, its applications and challenges are many. This work revolves around the application of bioinformatics in different contexts: basic ...
Psychosocial situation and work after breast cancer surgery : women's experiences
(2013-02-01)
Background: Breast cancer is the most common cancer among women. Nowadays, most women survive the disease, and many working women continue in paid employment. Nevertheless, there is little scientific knowledge of working ...
Somatostatin, dendritic cells and peptide T in psoriasis : a clinical, immunohistochemical and functional study
(2000-10-13)
Peptide T is an octapeptide designed to block the CD4 receptor. In a phase 1 study 9 psoriasis patients were treated with 2 mg peptide T i.v. once daily for 28 days and followed for a further 3 months. Five patients improved ...
Extremely preterm birth : brain imaging and outcome at early school-age
(2018-05-09)
and present in 37.1% of apparently healthy extremely preterm children and in 5.5% of term-born controls (adjusted odds ratio 7.92, 99% confidence interval, 3.69-17.20) at 6.5 years. Developmental coordination disorder was associated with various behavioral...
Reducing the morbidity of transurethral resection of the prostate based on patient selection, fluid absorption, and blood loss
(2001-10-05)
A higher long-term mortality due to myocardial infarction after TURP, compared to open surgery, irrigating fluid absorption and blood loss, prompted this investigation of whether prostate size has any correlation with ...
Complications following anterior cruciate ligament reconstruction
(2021-02-16)
Background: Venous thromboembolism (VTE) and septic arthritis (SA) are two rare complications following anterior cruciate ligament reconstruction (ACLR). Due to their rare incidence, risk factors and outcome are difficult ...
CYP2C-dependent drug metabolism in vivo : influence of genetics and drug interactions
(2010-11-24)
Cytochrome P450 enzymes (CYPs) are responsible for the metabolism of the majority of therapeutic drugs. This thesis focuses on one of the CYP subfamilies, CYP2C, especially CYP2C9 and CYP2C19, which are responsible for the ...