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Ulcerative colitis and cancer with special reference to the increased colorectal cancer risk
(1998-11-20)
The association between ulcerative colitis (UC) and cancer in a defined geographical region in Sweden was analyzed. UC patients have an increased overall risk of cancer of 40%, mainly due not only to the well-known increased ...
Sickness absence among patients with chronic pain in Swedish specialist healthcare
(2021-12-20)
Background: Chronic pain beyond three months is a global public health problem. Every third adult suffers from a chronic pain condition, resulting in a socioeconomic burden that corresponds to 3-10% of gross domestic product ...
Regulators of angiogenesis in diabetes and tumors
(2005-11-21)
Angiogenesis is tightly regulated in order to provide adequate supply of nutrients and oxygen for normal cellular function. Tissue oxygenation represents a balance between the requirement for oxygen to maintain the cellular ...
Inflammation and neurodegeneration in mouse nervous system : experimental application
(2006-01-26)
Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated inflammatory autoimmune disease of peripheral nervous system (PNS) and shares many of clinical, immunological, electrophysiological and morphological ...
Oxygen-dependent regulation of HIF-1alpha expression and function
(2009-09-04)
Hypoxia is a state of reduced oxygen levels below normal values. It occurs in the pathophysiology of many diseases and plays important roles in mammalian physiology and development. The hypoxia-inducible factors (HIFs) are ...
NF-kappaB in skin immune homeostasis and cancer development
(2009-08-03)
The outermost part of the skin, the epidermis, is built up by cells called keratinocytes. The epidermis provides a vital barrier between the body and the outer world. It is also a target for constant physical and microbial ...
Minimally-invasive breast interventions : methods for high yield, low risk, precision biopsy and curative thermal ablation
(2018-11-15)
Advances in medical imaging and the introduction of population-based screening programs have increased the detection rate and overall proportion of small breast tumors. In addition, progress in technology and medical ...
Patients with head and neck cancer : aspects on treatment, complications and rehabilitation
(2010-11-15)
Head and neck cancer is reported to be the fifth most common cancer globally and around 1,200 new patients are diagnosed in Sweden every year. Historically, survival rates have been rather constant but have started to ...
MicroRNAs in skin immunity and psoriasis
(2014-12-16)
The skin protects the organism from the environment and shields it from the constant danger of infections by microorganisms. Keratinocytes are epithelial cells in the skin that constitute a physical barrier towards the ...