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Studies on the structure, function and expression of phospholipase A2
(1998-10-29)
Phospholipase A2 (PLA2) enzymes are widely distributed and the enzymes possess different functions such as a role in digestion and inflammation. PLA2 catalyzes the hydrolysis of the sn-2 acylester bond of phospholipids, ...
Cortical plasticity in response to median nerve trauma
(2016-11-11)
Median nerve injuries in adults, repaired with nerve suture, lead to incomplete functional recovery despite improved surgical technique. This results in a reduction in quality of life, poorer working ability and a considerable ...
Cost analysis and policy implications in psychiatric care
(2009-04-01)
in Sweden in 2001 (Study I) was estimated at MSEK 85 774 (M€ 9 426, €1= SEK9.1). Indirect costs were totally predominant and constituted about 80% of the total cost, i.e. production losses due to early retirement, sickness absence and premature death...
Cardiovascular development of the preterm infant
(2016-09-16)
The numbers of preterm births and cardiovascular deaths are increasing in most countries. The causes of both developments are multiple and apparently not related to each other. However, preterm birth might provide an ...
Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control
(2000-11-24)
It is well known that, in children with type 1 diabetes, metabolic control often deteriorates during puberty. Better understanding of the mechanisms that cause deterioration of blood glucose control can lead to improved ...
Endothelial dysfunction in atherosclerosis and type 2 diabetes : clinical and molecular studies of the role of endothelin and arginase
(2018-05-08)
Background: Atherosclerosis is a modern world scourge and the number of people worldwide diagnosed with type 2 diabetes (T2D) is on the rise, causing much morbidity and mortality. Endothelial dysfunction (ED) is an early ...
Cell lineage analysis in humans
(2021-07-29)
Delineating a cell’s history, where it came from and what has happened to it, can provide clues as to how tissues and organs are formed and function in the healthy state and in disease. The gold standard for tracing the ...
Oesophageal cancer : on surgery and aetiology
(2010-05-14)
Oesophageal cancer is a common type of cancer with a dire prognosis. It
is globally the eight most frequent malignancy and the sixth leading
cause of death from cancer. The doctoral research described in this
thesis has ...
Regulation of gene expression by non-protein-coding RNAs
(2009-01-29)
The human genome sequencing projects revealed that the human genome contains over 3 billion DNA base pairs, but only 20,000 25,000 protein-coding genes. In fact, only about 1.2% of the genome codes for proteins. Surprisingly, ...
E-epidemiology : adapting epidemiological methods for the 21st century
(2009-08-28)
The traditional methods in epidemiological data collection are both costly and time consuming and less convenient for longitudinal large-scale studies. During the last decades, epidemiological studies suffer from low ...