Search
Now showing items 1-10 of 17
Immunological mechanisms in atopic dermatitis : clinical and experimental studies
(1998-11-13)
The aim of the study was to investigate immunological mechanisms in atopic dermatitis. Serum IgE levels are elevated in 80% of atopic dermatitis patients and CD4+ T cells and environmental allergens are known to be of importance in the pathogenesis...
Molecular studies of hypothalamic food intake regulating systems and central myelination in two anorectic mouse models
(2016-05-20)
The aim of this thesis is to increase the understanding of the hypothalamic mechanisms that are vital for food intake regulation, in particular as it relates to anorexia, and the molecular mechanisms underlying myelination ...
Leukotriene A4 hydrolase : identification of amino acid residues involved in catalyses and substrate-mediated inactivation
(2001-09-14)
Leukotriene (LT) A4 hydrolase catalyzes the committed step in the
biosynthesis of LTB4, a classical chemoattractant and immuine-modulating
lipid mediator involved in inflammation, host-defense against infections,
and ...
Distal radius fractures : epidemiology and aspects of surgical management
(2020-11-06)
Distal radius fractures (DRFs) are the most common fractures treated by physicians. About 20% of all DRFs are treated surgically. The main surgical methods are volar plate fixation, external fixation and percutaneous ...
Renal cell death in urinary tract infections : role of E. coli toxins
(2005-01-28)
model of fetal growth retardation induced by antenatal exposure to excess dexamethasone (DEX). We isolated renal proximal tubular cells (PTCs) from 20-day-old offspring in DEX-exposed-group (DEX-cells) and control-group (CON-cells). After 4 days...
Atrial fibrillation and lifestyle factors with focus on physical activity and alcohol consumption
(2017-02-06)
The overall aim of this thesis was to investigate how modifiable lifestyle factors, with a focus on alcohol consumption and physical activity, influence the risk of atrial fibrillation (AF). The thesis is based on data ...
Environmental risk factors for autism spectrum disorders
(2013-04-04)
Aims: Two overarching hypotheses were tested in this thesis- first, that the environmental factors studied during pregnancy or the time preceding birth would be associated with a higher risk of autism spectrum disorders ...
Cardiovascular disease in dementia
(2016-12-08)
The objective of this thesis was to characterize the burden of cardiovascular diseases in patients with dementia, their treatment and association with survival. Further, we aimed to explore whether cardiac structure in ...
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(2018-11-15)
Surgery is standard treatment for early stage endometrial cancer (EC), the most common gynaecological malignancy in developed countries. Traditionally, surgery has been performed by laparotomy (LT). Comprehensive surgical ...
Getting in and out of shape : relevance for organ formation and cancer
(2014-09-11)
A central question during development is how single cells form functional multi-cellular organ structures. The high reproducibility indicates intricate synchronization of cellular behaviors such as migration, proliferation ...