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Cancer risks in Swedish pesticide applicators in agriculture, forestry and gardening : a toxicological and epidemiological approach
(1998-10-23)
decades, and are thought to be risk factors of malignant lymphoma (Hodgkin's disease, non-Hodgkin's lymphoma), and soft tissue sarcoma; (6) test the hypothesis that exposure to phenoxy acid herbicides and chlorophenols is a risk factor of malignant...
Cell lineage analysis in humans
(2021-07-29)
Delineating a cell’s history, where it came from and what has happened to it, can provide clues as to how tissues and organs are formed and function in the healthy state and in disease. The gold standard for tracing the ...
Extracellular matrix-mediated signaling in the regulation of vascular smooth muscle cell phenotype and function
(2001-08-10)
Cardiovascular disease is the leading cause of mortality in the world. Even though death rates are today dropping in the developed countries, disability due to the disease is rising worldwide. The major portion of ...
Investigation of the genetic basis of familial non-BRCA1/2 breast cancer
(2005-12-30)
tumours identified chromosome 6 as a candidate locus for two non-BRCA1/2 families. Breast cancer in families 6006 and 6043 was linked to a 43.8 Mb region on chromosome 6, with suggestive LOD scores of 1.48 and 0.78 in the region for families 6006 and 6043...
Prognostic and predictive factors in Vietnamese breast cancer : a comparison with Swedish patients and effect on survival
(2012-03-07)
. The ER(+) rate was higher in premenopausal but lower in postmenopausal Vietnamese patients as compared to Swedish patients (71.1% vs. 58.4%, 44.7% vs. 71.6%, respectively). The PgR(+) tumors were found in 57.8% of pre- and 24.7% of postmenopausal...
Metabolic monitoring in patients undergoing cardiac surgery using intravascular microdialysis
(2016-04-22)
Critically ill patients and patients undergoing cardiac surgery often experience hyperglycemia, hypoglycemia and glycemic variability (fluctuating blood glucose concentrations), all of which have been associated with adverse ...
Dietary effects on gene regulation and function in human adipose tissue in obesity
(2007-05-04)
Obesity is an excess of body fat that develops from both genetic and environmental factors, leading to a disturbed balance between energy intake and energy expenditure. It is closely associated with insulin resistance, ...
Epidermal stem cells at the point of no return
(2023-05-17)
The skin is our main barrier against outside harm, and it helps to maintain internal
homeostasis. These functions are mostly fulfilled by the epidermis, which is the
outermost layer of the skin, formed from keratinocytes ...
Lost in transition? A study of newly graduated teachers' experiences during the initial period of employment
(2011-04-06)
The most crucial factors affecting burnout and work engagement when entering employment were feelings of competence to satisfactorily perform one’s work, the discrepancy between previous expectations and the actual conditions ...
Identification of novel modulators of protein synthesis and nucleolar biology using high throughput phenotypic screens
(2022-02-23)
Protein synthesis and ribosome biogenesis are fundamental steps in gene expression and constitute the most energy demanding processes in living cells. Dysregulation of these processes is associated to a variety of human ...