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The influence of quartz and surfactant on immune responses
(1998-04-17)
expression of complement receptors (CR), made functional analyses of metabolic activity, phagocytosis and adhesion, and evaluated morphology.
Resting blood granulocytes incubated with a porcine surfactant preparation had an increased expression of CR3...
Transcriptional profiling of the kidney glomerulus
(2010-05-20)
The kidney glomerulus plays a crucial role in ultraltration of the blood through the glomerular capillary wall. Glomerulus injury may occur in many systemic and primary kidney diseases or as secondary eects to drugs and ...
Chemical genetics and immunomodulation in Salmonella enterica serovar typhimurium infection
(2015-04-08)
Salmonella sp. are versatile bacteria that survive and replicate in a plethora of environmental
niches and hosts, including humans. The illnesses caused by various serovars in humans
range from mild gastroenteritis to ...
Pathophysiological characterization of traumatic brain injury using novel analytical methods
(2023-05-02)
Severity of traumatic brain injury is usually classified by Glasgow coma scale (GCS) as “mild”, "moderate" or "severe’, which does not capture the heterogeneity of the disease. According to current guidelines, intracranial ...
Assessment of environmental contaminants' neurotoxicity : in vitro and in vivo experimental studies
(2011-09-06)
Accumulating evidence over several decades shows that environmental contaminants may lead to neurodevelopmental alterations. An essential prerequisite to prevention is recognition of a chemical‟s ability to harm the ...
Misoprostol as a family planning drug : use in pregnant and non-pregnant women
(2014-10-28)
Background: Availability of comprehensive family planning services is fundamental in improving and ensuring women’s right to life and health. An estimated 222 million women have an unmet need for contraception, and 43.8 ...
Factors associated with lung function impairment in children and adults with obstructive lung disease
(2008-05-14)
was a risk factor for asthma symptoms, girls with asthma symptoms showed a larger negative effect on exhaled flows, at least in the four first years. In paper 3 and 4, we studied symptom data from 45,000 twins from the Swedish Twin Registry to quantify...
Quantifying cancer patient survival : extensions and applications of cure models and life expectancy estimation
(2013-10-18)
Cancer patient survival is the single most important measure of cancer patient care. By quantifying cancer patient survival in different ways further insights can be gained in terms of temporal trends and differences in ...
Time resolved functional brain networks : a novel method and developmental perspective
(2022-01-28)
Functional neuroimaging has helped elucidating the complexity of brain function in ever more detail during the last 30 years. In this time the concepts used to understand how the brain works has also developed from a focus ...
Effect of cycline-dependent kinase and matrix metalloproteinase inhibitors on hematopoietic and leukemic cells
(2008-10-24)
by roscovitine was consistent with apoptosis. Loss of mitochondrial membrane potential, release of cytochrome c, active fragment of caspase-3 and cleaved PARP were observed in all three cell lines, however, the pattern of activation of caspase-2 and -8 showed...