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Studies on human polyomavirus infection in association with central nervous system disorders and bone marrow transplantation
(1998-05-22)
Human polyomaviruses BK virus (BKV) and JC virus (JCV) do not generally cause diseases in healthy immunocompetent individuals. However both BKV and JCV can establish persistent infections that can be reactivated and ...
The matter of white and gray matter in cognitive impairment
(2017-08-03)
Cognitive impairment spans from minor subjective cognitive impairment to disabling dementia. Many biomarkers have been developed to monitor different aspects of cognitive impairment. Magnetic resonance imaging is the most ...
Dust mite allergens : cloning, characterisation and T-cell responses
(2001-03-09)
The number of allergens that have been cloned has increased dramatically
during the last 10 years, and today, over 400 allergen sequences are
available in the databases. In addition, at least 15 dust mite allergens
have ...
Epidemiological studies on breast cancer risk factors and screening
(2023-09-27)
This thesis aims to enhance cancer prevention by investigating the factors and outcomes associated with false-positive (FP) mammography recalls, as well as understanding the association between breast cancer risk factors ...
Endometriosis and ovarian reserve : inflammation and prognostic markers
(2008-04-18)
Introduction: Endometriosis is a common, benign gynecological disease,
associated with pelvic pain and infertility. It is generally thought to
be caused by retrograde shedding of menstrual tissue with subsequent
attachment ...
Factors affecting attendance at population-based mammography screening
(2002-01-11)
. Non-attendance was more likely among women who smoked regularly, had not visited a doctor in 5 years, had never had cervical smear tests, had never used oral contraceptives or hormone replacement therapy, never drank alcohol, and who reported no breast...
Determination of transcription factor binding specificities
(2015-11-19)
The term "genetic code" refers to the way in which the information encoded in nucleic acids
is converted into the amino-acid sequence of proteins. There is however also a second genetic
code, one that is used by the cells ...
Physical workload and exit from the labour market : epidemiological studies with a focus on employees with musculoskeletal disorders
(2022-10-28)
, men: OR 4.04 95% CI 2.00–8.15 and women: OR 3.25 95% CI 1.81–5.83) than when summing the risks of the single exposures (study II). However, the results of the synergy index (SI) for additive interaction were not statistically significant...
Factors affecting growth, differentiation and apoptosis of osteoblastic and osteosarcoma cells
(2008-10-17)
Osteoblasts play a fundamental role in determining bone structure and function. These cells originate from mesenchymal stem cells (MSCs) and through proliferation and differentiation develop into preosteoblasts and then ...
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
(Nature Publishing group, 2022-08-18)
Heart failure (HF) is a major cause of morbidity and mortality worldwide, highlighting an urgent need for novel treatment options, despite recent improvements. Aberrant Ca2+ handling is a key feature of HF pathophysiology. ...