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Presence of extrathyroidal TSH-receptor, with special reference to its role in neonatal regulation of lipolysis
(1998-03-13)
At birth, the newborn child must utilize stored energy until lactation is established. The main source of energy is fat - that is, triglycerides stored in the white adipose tissue. This study deals with hormonal regulation ...
Associations of breast cancer risk prediction tools with tumor characteristics and metastasis
(2020-04-23)
Purpose: The association between established risk factors for breast cancer and subtypes or prognosis of the disease is not well known. We analyzed whether the Tyrer-Cuzick–predicted 10-year breast cancer risk score (TCRS), ...
Pathogenesis of type 2 diabetes with emphasis on the mechanism of insulin resistance
(2006-09-15)
Type 2 diabetes is characterized by chronic hyperglycemia and develops slowly through stages of early impairments of glucose metabolism. The disease is often associated with obesity, physical inactivity, decreased insulin ...
The effect of alpha-HGA on HIV-1 replication
(2009-03-13)
Different classes of anti HIV-1 drugs are now available for treatment of HIV-1 infection. Although improved, these drugs show adverse effects and their long-term efficiency is severely hampered by the emergence of resistant ...
Psychosocial factors and preterm birth : national register-based studies
(2017-06-29)
Every year, approximately fifteen million infants are born preterm, defined as prior to 37 gestational weeks. Preterm birth is the number one cause of neonatal mortality, which kills more than one million babies every year ...
Genetic epidemiology of adiposity and abnormal glucose tolerance in South Asian Indians
(2013-08-12)
and subcutaneous adipose tissue (SAT) proxies led to an investigation of the differences in abdominal adiposity depots in Indians compared to Caucasians, using dual energy X-ray absorptiometry (DXA) as described in Paper V. Compared with a BMI-, gender- and age...
Functional and genetic studies in type 2 diabetes and obesity
(2013-11-14)
Type 2 diabetes (T2D) and obesity are highly prevalent disorders reflecting a complex interplay of genetics, epigenetics, and environment. They constitute serious health problems and lead to significant morbidity and ...
Regulatory networks of c-di-GMP signalling involved in biofilm formation, motility and host pathogen interactions in Salmonella typhimurium
(2013-08-09)
Adaptation to altered environmental conditions is one of the fundamental bacterial characteristics. The ubiquitous second messenger c-di-GMP plays a key role to adopt bacterial behaviour. Transition from motility to sessility ...
PET studies of the serotonin system in major depression and its treatment
(2014-10-03)
The serotonin system has been implicated in major depression since the
1960s, mainly based on the serotonin enhancing properties of
antidepressants. Positron emission tomography, PET, is the in vivo
molecular imaging ...
Rheumatoid arthritis as a modifier of periodontitis
(2007-01-19)
Periodontitis is a chronic tissue-destructive condition in which the
tooth-supporting collagen fibers of ligament and bone are broken down
mainly by the host s overreactive immune inflammatory response. The
relation between ...