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Assisted reproduction technology in men with ejaculatory dysfunction with special reference to spinal cord injury
(1998-05-16)
Background: Men afflicted by spinal cord injury (SCI), myelomeningocele (MMC) and testicular cancer (TC) with retroperitoneal lymph-node dissection (RPLND) share the problem of infertility due mainly, but not exclusively, ...
Vascular related pathologies in cardiovascular disease and cancer
(2017-04-28)
progenitor cells contribute to the injured vasculature and aid in the repair process. Yet the mechanisms underlying the amalgamation of the cells to the endothelium, their origin and functions have not been clear. Through Study 1 using animal models...
Functional investigation of prognostic biomarkers and therapeutic targets in glioma brain tumors
(2018-04-06)
to elucidate the function of PROX1 in glioblastoma. PROX1 mRNA was significantly lower in tumors with a mesenchymal signature, and its modulation in cultures derived from a heterogeneous glioblastoma tumor, transitioned the cells between non...
L-DOPA-induced signaling pathways and neuroepigenetic mechanisms in experimental parkinsonism and dyskinesia
(2014-11-07)
monophosphate (cAMP)/cAMP-dependent kinase (PKA)/ dopamine- and cAMP-regulated phosphoprotein of 32 kDA (DARPP-32) pathway. This exaggerated response results in excessive activation of the downstream extracellularregulated kinases 1 and 2 (ERK1/2) and mammalian...
Epidemiological and clinical aspects of fertility and diseases associated with infertility among Swedish-born and foreign-born women
(2007-05-18)
Objective: To examine the association between sociodemographic factors and first birth country of birth and hospitalization for pelvic inflammatory disease (PID), ectopic pregnancy (EP), infertility trends in Sweden during the 90s (study 1...
Genetic and immunological mechanisms regulating neuroinflammation
(2010-10-27)
Multiple sclerosis (MS) is the most common neurological disorder in young adults and imposes both health and socioeconomic burdens on society. The cause and aetiology of MS are incompletely understood and current treatments ...
Attempted suicide and shame
(2012-02-02)
A suicide attempt constitutes not only a risk factor for suicide, but also an expression of human suffering. As therapists, physicians and caring personnel we have an opportunity to reach out to this suffering individual ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
in women ≥40 years, both after spontaneous onset (aOR 1.71 95%CI 1.59-1.85), and induction of labor (aOR 1.45, 95%CI 1.28-1.65). We found no significant difference in rate of OASIS, episiotomy or low Apgar score. Overall, 79% of women ≥40 years had a...
Cardiovascular disease risk among people living with HIV in South Central Uganda
(2022-10-21)
October 2018 and January 2019 as part of the 19th survey round of the RCCS. Study I included a total of 1,968 participants (990 participants living with HIV and 978 HIV-negative participants), study II 423 participants living with HIV, and 1...
Small artery dysfunction : focus on preeclampsia and end-stage renal disease
(2012-04-18)
Background: End-stage renal disease (ESRD) and preeclampsia (PE) are associated with high risk of cardiovascular events and characterized by endothelial dysfunction. Resistance arteries are actively involved in the control ...