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Magnetic resonance imaging of rectal tumours
(1997-11-21)
Cross sectional imaging techniques introduced during the last two decades have been increasingly used in the evaluation of patients with pelvic tumours. The extent of tumour - the tumour stage - at the time of diagnosis ...
Lipid-related genes and their associations with coronary heart disease
(2014-04-25)
Coronary heart disease (CHD) is a complex disease caused by the long-term progression of atherosclerosis. Lipids, including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and ...
Do-Not-Attempt-Cardiopulmonary-Resuscitation decisions in the hospital setting
(2021-10-01)
Background: A Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order can be placed when CPR is not in accordance with the patient’s will, when CPR is considered not to benefit the patient, or when CPR is very unlikely ...
Human parvovirus B19 : studies on the pathogenesis of infection
(2001-05-11)
Human parvovirus B19 (B19) causes the common childhood disease erythema infectiosum. The virus is transmitted by the respiratory route, infects erythroid progenitor cells, and thereby inhibits erythropoiesis. The seroprevalence ...
Genetic studies in familial non-BRCA breast cancer
(2017-11-09)
Family history is an important risk factor for breast cancer, the presence of breast cancer in a first degree relative in general nearly doubles the risk and the risk increases with the number of affected relatives. ...
Biopsies, diagnosis and prognosis in prostate cancer
(2011-11-01)
Prostate cancer is the third most common cancer in men worldwide, and poses a challenge both for patients and health care systems. Many aspects of prostate cancer are controversial, from screening for early detection to ...
Pancreatic ductal adenocarcinoma : computed tomography for diagnosis, local staging and prediction of postoperative complications
(2015-04-30)
Pancreatic ductal adenocarcinoma (PDAC) is a disease with a dismal prognosis, being the 4th
leading cause of cancer deaths in Sweden and worldwide. The only potentially curative
therapy is surgery. Unfortunately, by the ...
Structural enzymology of oxalate degradation in Oxalobacter formigenes
(2008-01-04)
Oxalic acid, as one of nature's most highly oxidised compounds, is toxic
to most organisms. It is introduced in the human body in the diet but
also as a waste product of cellular metabolism. Mammals do not posses ...
Envelopment of retrovirus and vaccinia virus
(2001-08-10)
This thesis describes envelopment of retrovirus and vaccinia virus. Retrovirus envelopment, i.e. budding, occurs from the plasma membrane (PM) of infected cells in an environment that is abundant with cellular proteins. ...
L-DOPA-induced signaling pathways and neuroepigenetic mechanisms in experimental parkinsonism and dyskinesia
(2014-11-07)
In patients with Parkinson’s disease (PD), the restoration of depleted striatal dopamine by chronic administration of its precursor, L-DOPA, results in the emergence of debilitating involuntary movements. This complication, ...