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Analysis of human epidermal Langerhans' cells and allergens with confocal laser scanning microscopy
(1997-10-31)
The aim of the thesis was to explore confocal laser scanning microscopy (CLSM) as a tool for 1) quantitative and 3-dimensional (3-D) analysis of the human antigen-presenting Langerhans' cell (LC) in epidermis and 2) for ...
Diabetes mellitus, socioeconomy and self-rated health : population-based studies in cohorts registered in the diabetes incidence study in Sweden
(2001-02-26)
$ 4743 among
men and US$ 4976 among women (1997 prices). Hospital inpatient care
accounted for more than 50 percent of the excess costs. Eight years after
diagnosis, the excess costs were US$ 2010 among men and US$ 2734 among
women. The higher costs...
Tissue distribution studies and risk assessment of perfluoroalkylated and polyfluoroalkylated substances (PFASs)
(2013-05-15)
Perfluoroalkylated and polyfluoroalkylated substances (PFASs) represent a large class of man-made chemicals. These substances have emerged as environmental contaminants due to their extraordinary resistance to degradation, ...
Trajectory mapping of human embryonic stem cell cardiogenesis reveals lineage branch points and an ISL1 progenitor-derived cardiac fibroblast lineage
(2021-02-17)
A family of multipotent heart progenitors plays a central role in the generation of diverse myogenic and nonmyogenic lineages in the heart. Cardiac progenitors in particular play a significant role in lineages involved in ...
Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight
(2018-08-17)
Prematurity affects more than 10% of infants worldwide and is the main reason for neonatal mortality. Improvements in neonatal care have led to higher survival rates into adulthood. Adverse events during organogenesis and ...
PET studies of the serotonin system in major depression and its treatment
(2014-10-03)
The serotonin system has been implicated in major depression since the
1960s, mainly based on the serotonin enhancing properties of
antidepressants. Positron emission tomography, PET, is the in vivo
molecular imaging ...
Platelet function in diabetes mellitus : relationships to hyperglycaemia, antidiabetic treatment and microangiopathy
(2005-01-14)
Diabetes mellitus is associated with accelerated atherosclerosis and increased morbidity and mortality in micro-and macrovascular complications. The metabolic derangements that accompany diabetes can adversely influence ...
Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives
(2010-05-14)
Genetic hemochromatosis (GH) is an autosomal recessive disease caused by
a C282Y mutation in the HFEgene, and is characterized by excess iron
accumulation in multiple organs. Classical manifestations of GH include
liver ...
Assessment of cognitive function in elderly patients with hip fractures
(2007-03-09)
Impaired cognitive function is common among elderly patients. The aim of this thesis was to illuminate the documentation of cognitive function in elderly patients with hip fractures and to study the effect of cognitive ...
Dysglycaemia and cardiovascular disease. Aspects on screening, management, and prognosis
(2023-03-24)
Background: Dysglycaemia, in this thesis defined as impaired glucose tolerance (IGT) or type 2 diabetes (T2DM), is a major risk factor for cardiovascular disease (CVD). International guidelines recommend screening for ...