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MHC-class I restricted peptide-based immunomodulation of CD8+ T and NK cells
(2012-09-06)
The main aims of the immune system are to protect the host from potential threats by distinguishing self from non-self and altered-self. T cells and NK cells play a key role in the identification and elimination of threats ...
Anti-diabetic effect of gynostemma pentaphyllum tea in type 2 diabetes
(2011-10-13)
Type 2 diabetes mellitus (T2D) is a major non-communicable disease and an important health burden worldwide, especially in the developing countries including Vietnam. Gynostemma pentaphyllum has been widely used in Vietnam as a herbal medicine...
Markers of inflammation and neurodegeneration in muliple sclerosis
(2012-08-30)
nor total T2 lesion load. This paper supports the possibility that infratentorial T2 lesion load is associated with OCB in CSF....
Treatment of displaced proximal humeral fractures in elderly patients
(2011-05-06)
The optimal treatment for patients with displaced fractures of the proximal humerus, especially elderly patients with osteoporosis, is still controversial. For the 2- and 3-part fractures according to the Neer classification, there is a trend...
Importance of pharmacogenetic and environmental factors for variation in caffeine disposition : with special emphasis on CYP1A2, CYP2A6, NAT2 and XO
(2012-03-12)
). Phenotyping of CYP1A2, CYP2A6, NAT2 and XO was performed using caffeine as a probe drug and measuring concentration of parent compound and its metabolites in plasma or urine samples. CYP1A2 activity was estimated by 17X/137X plasma ratio, and CYP2A6, NAT2...
Pharyngeal surgery and epidemiology in sleep apnea
(2012-08-13)
Obstructive sleep apnea syndrome (OSAS) occurs frequently among adults and children. The first-line treatments in adults are continuous positive airway pressure (CPAP) or mandibular retaining devices (MRDs), but the long-term ...
Aetiology in community-acquired pneumonia
(2012-11-08)
in those infected with other classical bacteria (1.18 vs. 0.18, P=0.038), in patients with pneumococcal as compared to viral aetiology (2.43 vs. 0.24, P=0.017), and in patients with PSI classes 4-5 (2.07) than in those with PSI classes 1-3 (0.52, P=0...
Measurements of physical workload with special reference to energy expenditure and work postures
(2011-01-27)
oxygen consumption (VO2) measurements (Study I) performed at 25 workers’ workplaces. Two data-analysis methods were tested: 1) direct HR measurements expressed in beats per minute (bpm), and 2) HR measurements combined with individual exponential HRVO2...
Cancer and calcium : epidemiological studies of cancer incidence and survival
(2011-03-15)
Studies have shown that there could be an association between dietary calcium and cancer, and more specifically it has been suggested that serum calcium is involved in the etiology of cancers of the prostate. In order to ...
Child injury in Europe : scope, circumstances and association with country-level housing conditions and economic disparities
(2012-02-22)
department-attended child non-fatal home injuries for 0-18 years based on an average of six European countries was estimated at 44.9 (95% CI 29.1-60.7) per 1,000 inhabitants, with the incidence peaking at one to two years. The characteristics...