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Heart rate variability in patients with stable angina pectoris
(2009-01-16)
The rate and modulation of the heart beat (i.e. heart rate variability; HRV) are controlled by the autonomic nervous system. Cardiac sympathetic activation decreases and parasympathetic increases HRV. Measurements of HRV ...
Studies on hereditary spastic paraplegia proteins
(2010-05-14)
The hereditary spastic paraplegias (HSPs) are a clinically and genetically diverse group of inherited neurological disorders that primarily cause progressive spasticity and weakness in the lower limbs due to a length-dependent, ...
Studies of cannabinoid receptor 1 in mantle cell lymphoma
(2008-11-21)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects
older individuals and has a male predominance. MCL has one of the worst
prognoses among lymphomas and currently there is a search for a curative
therapy. ...
Structural maintenance of chromsomes : a complex tale of genomic integrity
(2009-04-03)
Genomic integrity is an absolute requirement for cell survival.
Programmed events such as genome rearrangements and DNA replication can
cause lesions in the DNA, as can exogenous agents such as radiation and
chemicals. ...
Body and soul : studies on health and psychosomatic complaints among adolescents in Sweden
(2008-10-07)
Objective: The aim of this thesis is to describe the health of the
adolescents with special emphasis on psychosomatic complaints.
Method: Both quantitative and qualitative methods were used to get a
insight into ...
Paroxysmal atrial fibrillation : prognostic implications
(2008-08-29)
This thesis is based on data from the Stockholm Cohort on Atrial
Fibrillation (SCAF). This cohort consists of all 2912 patients with
atrial fibrillation or flutter who were treated as in or outpatients at
South Hospital ...
Development of novel DNA vaccine and immunotherapeutic approaches
(2009-08-06)
Many potential DNA vaccination and immunotherapeutic strategies has been explored in both animal models and human settings in recent years. However, the failure of efficient and safe method development suggests that it is ...
Studies on syndecan-1 in mesenchymal tumors
(2010-01-08)
The syndecans are a four-member family of type I transmembrane proteoglycans. Their core proteins have a short cytoplasmic domain, a transmembrane domain and a large N-terminal extracellular domain possessing glycosaminoglycan ...
Role of genes and environment for the development of rheumatoid arthritis : results from the Swedish EIRA study
(2009-01-09)
Rheumatoid arthritis (RA) is a complex disease with autoimmune features primarily causing destruction in the joints of the body. Knowledge regarding risk indicators and causes are increasing but so far only a few genetic ...
Studies on female genital tract infections and the role of nitric oxide in diagnosis
(2010-04-16)
Female genital tract infections are among the most common conditions causing individuals to seek medical care, and are associated with a high gynaecologic and reproductive morbidity. Thus, prompt and precise diagnosis of ...