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Biomarkers of suicide risk in psychosis
(2009-11-27)
was to investigate the long-term suicide risk in schizophrenia spectrum psychosis, whether concentrations of the CSF monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) are related to suicidal behavior and to the overall mortality...
DNA microarray approaches to understanding the regulation and evolution of gene expression networks
(2009-09-24)
regulatory networks involved in the pheromone response (Paper II) and investigate the role of Gcn5 transcription co-regulator, a histone acetyltransferase (HAT), in re-programming gene expression during the salt stress response in fission yeast (Paper III...
Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(2010-02-05)
the atrophy factors that contributed most significantly to the diagnoses with correct AD classification of 90.2%. The correct classification of AD+CVC from controls increased from 79.5% (only CSF biomarkers) to 84.6% (combined CT measurements with CSF...
Nurses in paediatric care : competence, professional identity and research utilization
(2010-04-08)
Paediatric health care is becoming highly specialized and there is a need of nurses with specialist knowledge in the field. A large turnover of personnel and shortage of specially trained paediatric nurses have resulted ...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
The aim of this thesis is to evaluate the influence of renal dysfunction on the presentation for myocardial infarction (MI), its treatment and outcome. Patients between 2003 and 2006 were selected from the nationwide Swedish ...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
occurrence of psychoactive plant use in Sweden. Studies were done in attempt to elucidate the metabolic pattern of α- and b-asarone in humans. Cis(b)-2,4,5-trimethoxycinnamic acid was regarded to be the most abundant metabolite, evidence of a hydroxylated...
Exploring a national practice-based register for the management of rheumatoid arthritis
(2008-10-17)
Rheumatoid arthritis (RA) is a chronic, inflammatory, auto-immune disease with an unpredictable and debilitating course. From diagnosis and onward, RA patients who need treatment with anti-rheumatic drugs will require ...
Role of genes and environment for the development of rheumatoid arthritis : results from the Swedish EIRA study
(2009-01-09)
Rheumatoid arthritis (RA) is a complex disease with autoimmune features primarily causing destruction in the joints of the body. Knowledge regarding risk indicators and causes are increasing but so far only a few genetic ...
Hidradenitis suppurativa : clinical studies with focus on evaluation
(2010-04-02)
Hidradenitis suppurativa (HS) is a chronic inflammatory disease of mainly
unknown aetiology which in most cases involves axillae or groins and that
can last for decades. In this thesis different clinical aspects of HS ...
Tissue biomarkers in prostate cancer
(2009-09-25)
Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely ...