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Studies of diagnosis and differential diagnosis in primary aldosteronism
(2010-05-14)
the histopathologic examination, can be uncertain. Unilateral adenoma and bilateral hyperplasia are the most common subtypes. With in situ hybridization, expression of the gene CYP 11B2 encoding for enzymes involved in aldosterone synthesis can be visualized...
Cardiovascular disease prevention after spinal cord injury : a new challenge
(2010-05-07)
Spinal cord injury (SCI) typically leads to permanent infralesional motor
and sensory functional losses, pathophysiological aberrations in most
organ systems and a lasting vulnerability for a variety of complicating
conditions. ...
Isoforms of mammalian glutaredoxin 2
(2009-05-05)
lies upon the question how Grx2 activity is regulated as well as how many isoforms of mammalian glutaredoxin 2 there are. Here, we have characterized human Grx2 as the first iron sulfur centercontaining thiol-disulfide oxidoreductase of the thioredoxin...
Prevention of mother-to-child transmission of HIV-1 using antiretroviral drugs in Dar Es Salaam, Tanzania
(2009-08-21)
for their efficacy to prevent MTCT of HIV in HIV-1-infected pregnant women in Uganda, Tanzania, and South Africa (the Petra trial). In group A treatment was given antepartum for 2 weeks, intrapartum and postpartum for 7 days to mother and infant. In group B...
Mechanism of pathological angiogenesis in adipose tissue and tumor
(2009-09-18)
and further investigation of mechanism of angiogenesis in adipose tissue metabolism and cancer development. Multiple factors spatiotemporally regulate adipogenesis and angiogenesis. In a transgenic mouse model described in the first constituent paper, FOXC2...
Synaptic plasticity in local networks of neocortical layer 2/3
(2008-12-26)
-timing dependent plasticity, STDP). We reported that the learning rule governing STDP modification is regulated by preceding activity in a postsynaptic neuron. Moreover, we have shown that the difference between STDP observed at layer 2/3 (L2/3) P-P cell...
Wnts in development : focus on midbrain
(2009-01-16)
Studies in the field of embryonic development reveal the temporal and
spatial requirement of specific genes/proteins in the formation of a
given tissue. The specific knowledge of which genes/proteins regulate
development ...
Paroxysmal atrial fibrillation : prognostic implications
(2008-08-29)
This thesis is based on data from the Stockholm Cohort on Atrial
Fibrillation (SCAF). This cohort consists of all 2912 patients with
atrial fibrillation or flutter who were treated as in or outpatients at
South Hospital ...
Effects of an expanded rehabilitation programme in patients with ischemic heart disease
(2009-11-12)
. The primary composite endpoint was time to first cardiac event defined as CV death, MI or readmission due to CV disease. There was a significant reduction in the primary composite endpoint among those in the ECR as compared to UC group (47.7% vs. 60.2%; hazard...
Genetic content of clinical pneumococcal isolates and its relation to disease outcome
(2009-09-30)
Streptococcus pneumoniae is a Gram-positive bacterium that can cause a wide range of diseases. These include otitis media, sinusitis, pneumonia and meningitis. It can, however, also cause asymptomatic carriage thereby ...