Search
Now showing items 1-10 of 136
Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis
(2008-10-03)
Dengue fever (DF) is the most common global viral mosquito-borne infection, with 100 million estimated cases annually in tropical and subtropical areas. The dengue viruses (genus Flavivirus, Flaviviridae) occur in 4 serotypes ...
Alternative splicing of interleukin-7
(2009-04-03)
to function as either agonists or as antagonists of the wildtype cytokine. Interleukin-7 (IL-7) plays a non-redundant role in early stages of normal B and T-cell development; IL-7-receptor signaling is required for the maintenance of T-cell homeostasis...
Peripheral venous catheters : quality of care assessment
(2009-12-31)
About half of the patients admitted to hospitals receive intravenous
therapy through peripheral venous catheters (PVCs). Unfortunately, the
use of PVCs is associated with the risk of complications that may lead to
increased ...
Aspects on local recurrence of rectal cancer
(2009-04-09)
Rectal cancer is a common malignant disease in Sweden which is diagnosed in about 1,800 patients annually. Local failure, defined as residual or recurrent disease within the pelvis, is of major concern in rectal cancer ...
Storage and transfusion of platelets : in vitro and in vivo studies in healthy volunteers and in allogeneic hemapoetic progenitor cell transplant recipents
(2009-03-13)
Early studies in the 1960´s showed that platelet (PLT) transfusions
significantly reduced the incidence of fatal hemorrhages. Together with
the advances in the hematology and transplantation field, easily
accessible ...
Body and soul : studies on health and psychosomatic complaints among adolescents in Sweden
(2008-10-07)
Objective: The aim of this thesis is to describe the health of the
adolescents with special emphasis on psychosomatic complaints.
Method: Both quantitative and qualitative methods were used to get a
insight into ...
Investigation of genetic factors in multiple sclerosis
(2009-05-08)
, association analyses have disclosed several genes of interest in MS including IL7R, IL2RA, CLEC16A, CD58 and RPL5. The HLA association shows the strongest effect on risk for MS, odds ratio for the other genes are in the range 1.1 1.4. It is not known how many...
Studies on the phenotype of LXRβ-/- mice : from malabsorption to amyotrophic lateral sclerosis
(2008-10-06)
Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors
belonging to the superfamily of ligand-activated transcription factors
with a key role in the control of lipid and glucose metabolism. Studies
of the ...
Self-rated health : biobehavioral determinants with focus on inflammatory factors
(2010-05-28)
Self-rated (subjective) health is an independent predictor of future
mortality, but neither the mechanisms behind this relation nor the
biological determinants of poor self-rated health are known. Inflammatory
cytokines ...
Experimental combination therapy of brain cancer cell models
(2012-11-21)
Epigenetic alterations and aberrant expression of genes controlling epigenetic mechanisms have been identified in several cancers, including medulloblastoma and glioma, the most common primary brain tumors in children and ...