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Study of pruritus in psoriasis vulgaris : role of tachykinins
(2009-01-23)
Pruritus has not been considered as the most important symptom of
psoriasis. In the present thesis various methodologies have been used to
investigate this symptom in psoriasis.
The focus groups created a proper ...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
A new technique to assess dermal absorption of chemical vapor in vitro by thermogravimetric analysis (TGA)
(2008-11-28)
There is a huge lack of dermal uptake data for chemicals, and it is frequent with large variations in reported permeability coefficients for chemicals with more than one data set, showing the need for a new and standardized ...
New apheresis techniques in transplantation
(2008-11-21)
The shortage of organs for transplantation is a global problem and therefore it is of outmost importance to increase the number of donations and improve long term graft survival. As an effort to increase kidney donations, ...
The risk of malignancy in women with endometriosis
(2010-03-05)
and malignancy and control for parity. There were 3 822 incident cases of a malignancy recorded during follow up (paper II). The study showed a statistically significant increased risk of endocrine tumors (SIR1.38), ovarian cancer (SIR 1.37), kidney cancer (SIR 1...
Family studies of schizophrenia and pregnancy outcomes
(2008-12-26)
Why do psychiatric diseases run in families? Why do some women tend to have similar obstetric complications in subsequent pregnancies? The overall aim of this thesis was to investigate how genes and environments contribute ...
On angiogenesis modulation
(2009-08-28)
During evolution, the transition from unicellular to multicellular organisms required the origin of a transport system capable of interconnecting specialized cells throughout the body of the organism. In higher animals, ...
Studies of cannabinoid receptor 1 in mantle cell lymphoma
(2008-11-21)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects
older individuals and has a male predominance. MCL has one of the worst
prognoses among lymphomas and currently there is a search for a curative
therapy. ...
Effects of an expanded rehabilitation programme in patients with ischemic heart disease
(2009-11-12)
was offered physical training, education and heart school with information/counselling on risk factor intervention. The patients met with a cardiac nurse on one or two occasions after the event and a cardiologist on one occasion, 6-8 weeks after the event...
Exploring a national practice-based register for the management of rheumatoid arthritis
(2008-10-17)
Rheumatoid arthritis (RA) is a chronic, inflammatory, auto-immune disease with an unpredictable and debilitating course. From diagnosis and onward, RA patients who need treatment with anti-rheumatic drugs will require ...