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Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
Mortality and co-morbidity among patients with hemochromatosis and their first-degree relatives
(2010-05-14)
Genetic hemochromatosis (GH) is an autosomal recessive disease caused by
a C282Y mutation in the HFEgene, and is characterized by excess iron
accumulation in multiple organs. Classical manifestations of GH include
liver ...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
Mechanism of pure glucose-dependent insulinotropic activity of a novel imidazoline compound BL11282
(2008-05-01)
We developed a novel, pure glucose-dependent, insulinotropic imidazoline compound, BL11282, which directly affects the insulin exocytotic machinery and does not block the KATP channel activity. BL11282 does not induce ...
Molecular studies of Hutchinson-Gilford progeria syndrome
(2009-05-22)
Hutchinson-Gilford progeria syndrome (HGPS) is a very rare genetic disease, with an incidence of 1 in 4-8 million live births, that causes segmental premature aging in children. The children look normal at birth but begin to develop symptoms...
Studies on hereditary spastic paraplegia proteins
(2010-05-14)
The hereditary spastic paraplegias (HSPs) are a clinically and genetically diverse group of inherited neurological disorders that primarily cause progressive spasticity and weakness in the lower limbs due to a length-dependent, ...
Computer-supported diagnosis in psychiatry
(2009-02-20)
-based medicine perspective; 7) no major difference in terms of correctness of the proposed diagnosis was found between the computerized method and the manual method for diagnosis and where a difference was noted it was in favour of the manual method; and 8...
SARS coronavirus : the role of accessory proteins and nitric oxide in the replication cycle
(2008-08-28)
Severe acute respiratory syndrome coronavirus (SARS-CoV) caused the first
pandemic of the 21st century. The etiological agent was identified as a
novel coronavirus. Until then, human coronaviruses (HCoVs) had only ...
Storage and transfusion of platelets : in vitro and in vivo studies in healthy volunteers and in allogeneic hemapoetic progenitor cell transplant recipents
(2009-03-13)
Early studies in the 1960´s showed that platelet (PLT) transfusions
significantly reduced the incidence of fatal hemorrhages. Together with
the advances in the hematology and transplantation field, easily
accessible ...
Traffic noise and cardiovascular disease
(2010-04-30)
Traffic noise is an increasing problem in urban areas worldwide, but health effects in relation to traffic noise exposure are not well understood. Several studies show that noise may give rise to acute stress reactions, ...