Search
Now showing items 1-10 of 126
Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
-cell interactions of committed ectodermal cells. We also showed that expression of the Wnt PCP signalling gene Vangl2 (Van gogh-like 2) was increased. Wnt7a´s influence on neuronal differentiation was studied by investigation of β-tubulin III expression, a marker...
Teleost retina : a model to study neurogenesis and angiogenesis
(2009-03-09)
Teleost models, zebrafish and medaka have become popular models to study
various aspects of developmental biology and genetics. The rapid
embryonic development, transparent embryos and the availability of many
mutants ...
New apheresis techniques in transplantation
(2008-11-21)
The shortage of organs for transplantation is a global problem and therefore it is of outmost importance to increase the number of donations and improve long term graft survival. As an effort to increase kidney donations, ...
Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(2010-02-05)
Background: The brain atrophy in individual Alzheimer's disease (AD) patients includes not only specific atrophy from AD pathology, but also atrophy induced by normal aging and cerebral vascular diseases. Although medial ...
Genetic and functional studies on the thyroid hormone axis
(2008-10-24)
mutation, glycine 431 for serine in the first transmembrane segment. Functional properties of the mutant TSHr revealed constitutive activity when investigated during transient expression in COS-7 cells. There was no indication of autoimmune disorder. All...
Computer-supported diagnosis in psychiatry
(2009-02-20)
-based medicine perspective; 7) no major difference in terms of correctness of the proposed diagnosis was found between the computerized method and the manual method for diagnosis and where a difference was noted it was in favour of the manual method; and 8...
Tobacco smoking, high body mass index and the outcome after surgery : the role of intervention
(2008-11-07)
The negative effects of smoking and obesity on public health are
well-known. Despite this knowledge, the smoking-attributable morbidity
and mortality is estimated to rise rapidly in the forthcoming years, and
obesity ...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
Studies of cannabinoid receptor 1 in mantle cell lymphoma
(2008-11-21)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects
older individuals and has a male predominance. MCL has one of the worst
prognoses among lymphomas and currently there is a search for a curative
therapy. ...
Cell cycle and differentiation in Giardia Lamblia
(2008-04-30)
Giardia lamblia is the major cause of waterborne diarrhea worldwide.
Giardiasis is initiated by ingestion of cysts, which after passing
through the stomach are triggered to excyst. Excystation, or awakening
from dormancy, ...