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Smärta, infektion och återanpassning till livet efter en brännskada
(2010-01-22)
A burn injury is an unforeseen event that includes a physical as well as
a psychological trauma for the person afflicted. The trauma is
experienced differently by individuals as do perceived problems during
care, ...
Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
HIV-1 genotype and vertical transmission in northern Vietnam
(2008-10-28)
After 18 years from the beginning of the HIV-1/AIDS epidemic in Vietnam, the number of HIV-1 infected individuals is still increasing. Investigations conducted at two distinct time points in two separate groups of HIV-1 infected intravenous drug...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
convenient synthetic routes toward a wide range of 3-(arylthio)indoles in good yields. In an extension, the sulfonation of 1-(phenylsulfonyl)indoles and pyrroles using chlorosulfonic acid in acetonitrile has been studied, leading to development of a simple...
LXR and aromatase knock-out mice : animal models providing insight into human diseases
(2009-01-01)
In our characterization of mouse strains carrying mutations in nuclear
receptor and aromatase genes we have found phenotypes which resemble four
human diseases: benign prostatic hyperplasia (BPH), Sjögren s syndrome
(SS), ...
Characterisation of HMGB1 in inflammation
(2008-09-26)
High mobility group box chromosomal protein 1 (HMGB1) was discovered over three decades ago as a nuclear protein which is present in all mammalian nucleated cells. Subsequent studies have revealed additional properties of HMGB1 besides its...
Applications of nanotechnology in neuroscience : functionalized superparamagnetic nanoparticles as contrast enhancers in experimental magnetic resonance imaging
(2010-04-08)
Magnetic resonance imaging (MRI) is a noninvasive imaging technique that
helps clinicians not only to diagnose but also to plan the treatment of
invasive surgery and actually treat medical conditions. Superparamagnetic
iron ...
Early function of KCC2 and Wnt genes : cytoskeletal effects in neural stem cells
(2008-09-19)
From closure of the neural tube until formation of neuronal networks,
cells undergo several crucial changes which depend on the expression of
many important molecules. GABA, the principal inhibitory neurotransmitter
in ...
Studies on hereditary spastic paraplegia proteins
(2010-05-14)
different HSP proteins: atlastin-1, a member of the dynamin superfamily of large GTPases through sequence similarity, and maspardin Mast syndrome, spastic paraplegia, autosomal recessive with dementia. Mutations in the atlastin-1 gene, SPG3A, are the second...
Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives
(2009-11-06)
dihydropyrazolone, namely 4-cyano-1-cyanoacetyl-2-(cyclohexen-1-yl)-1,2-diazaspiro[4.5]decan-3-one, whose structure was confirmed by an X-ray analysis. Mild hydrolysis of this compound resulted in isolation of a des-cyanoacetylated product. In addition, prolonged...