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Aprotinin for reduction of bleeding and transfusions in patients on clopidogrel undergoing urgent coronary surgery
(2009-05-08)
-860) in the aprotinin group vs. 1210 mL (95%CI:860-1550) in the control group (p=0.004). The aprotinin group received fewer transfusions of packed red blood cells (0.9 U, 95%CI:0.1-1.7, vs. 2.7 U, 95% CI:1.4-4.1; p=0.01), platelets (0.1 U, 95%CI:0-0.3, vs. 0.6 U, 0.2- 0...
Elbow kinematics : studies of the elbow joint under normal conditions and after joint replacement
(2010-05-28)
Background: Total elbow arthroplasty (TEA) is used for treatment of
patients with severe pain and disability due to reumatoid arthritis. Long
term results are not as good as for hip and knee replacements. Further
development ...
Calcium signaling : molecular mechanisms and cellular consequences
(2008-11-21)
Cells exploit calcium (Ca2+) signaling to transmit information. In a
multicellular organism, each cell must be able recognize, process, and
respond to information received from the surrounding environment. In this
thesis ...
Psychopathic personality in adolescence : genetic and environmental influences
(2009-09-04)
Psychopathy, or psychopathic personality, is a personality disorder characterized by a constellation of deviant interpersonal, affective, and behavioral dimensions. It has consistently been shown that the psychopathic ...
Physiotherapeutic rehabilitation and lumbar fusion surgery
(2010-05-14)
-IV), 3, 6, 12 months (Study II) and 2-3 years after surgery (Studies II-III). In Studies II-IV, patients were randomised to psychomotor therapy (N=53) or exercise therapy (N=54) implemented during the first 3 post-operative months. Semi...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in children is 1-3%, with the peak...
Development of screening for primary immunodeficiency
(2009-09-04)
in paper III. The levels of complement protein C3 were measured in samples from a C3 deficient patients and controls. The levels of C3 in the control group was significantly higher than in the Swedish C3 deficient patient sample, indicating that serum...
Genetic and epidemiological studies of dystocia : difficult labour
(2008-12-19)
Objective: To explore the epidemiological characteristics, the influence
on reproductive health and the genetic basis of dystocia prolonged and
difficult labour.
Material and methods: The thesis has a retrospective ...
Sex steroid hormone receptors : inner ear and hearing
(2009-04-29)
It is well known that hearing loss is more profound in elderly males than
females, regardless of noise exposure. Also, an age-related hearing
decline starts much earlier in males, already after the age of 30, while
in ...
LXR and aromatase knock-out mice : animal models providing insight into human diseases
(2009-01-01)
In our characterization of mouse strains carrying mutations in nuclear
receptor and aromatase genes we have found phenotypes which resemble four
human diseases: benign prostatic hyperplasia (BPH), Sjögren s syndrome
(SS), ...