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On angiogenesis modulation
(2009-08-28)
of the resulting vascular plexus; iii) how sixteen genes and twenty-eight compounds modulating angiogenesis were identified, and a role for the serine/threonine (S/T) phosphatases PPP1CA, PPP1CC, and PPP4C was uncovered using – for the first time in vertebrates – a...
Experimental combination therapy of brain cancer cell models
(2012-11-21)
. Mono-therapy using HDACi sodium 4-PB induced minor cell killing effects in neither of the analyzed cell lines. Similar results were observed after mono-therapy using gefitinib or vandetanib. However the combination of 4-PB with gefitinib resulted...
The role of CYP3A4/5 in alprazolam metabolism
(2010-05-14)
Cytochrome P450 3A (CYP3A) enzyme family is involved in the metabolism of about 50 % of all drugs in clinical use. Among CYP3A, CYP3A4 and CYP3A5 are the major enzymes in adults; however CYP3A5 is polymorphic and primarily expressed in black...
Women who do not attend parental education classes during pregnancy or after birth
(2008-08-15)
, and 4,600 women were eligible for the study according to the Medical Birth Register. The number of responders to the first questionnaire was 3,061, to the second 2,762, to the third 2,563 and to the fourth 1,721. The representativeness of the sample...
Peripheral venous catheters : quality of care assessment
(2009-12-31)
About half of the patients admitted to hospitals receive intravenous
therapy through peripheral venous catheters (PVCs). Unfortunately, the
use of PVCs is associated with the risk of complications that may lead to
increased ...
Activities with balance limitations among patients with perpheral arthritis : description and assessment
(2008-08-25)
Background and aim: Patients with peripheral arthritis (PA) have several
impairments that can influence balance and be risk factors for falls and
fear of falling. Since disability varies among these patients, we need ...
Chest wall sarcomas
(2010-03-05)
Aim: To evaluate initial symptoms and clinical features, diagnosis and delay
in osteosarcoma (OS), Ewing sarcoma (EWS) and chest wall chondrosarcoma
(CS). To assess treatment and identify prognostic factors in chest ...
On the detection and management of urinary bladder carcinoma
(2008-11-07)
Aims: To describe the diagnosis and clinical course of an unselected population-based cohort of patients with newly diagnosed transitional cell carcinoma of the urinary bladder. To assess if random bladder biopsies and the ...
Study of the psoriasis proteome and analysis of MHC class I expression and function
(2008-05-15)
Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic ...
Studies on hereditary spastic paraplegia proteins
(2010-05-14)
The hereditary spastic paraplegias (HSPs) are a clinically and genetically diverse group of inherited neurological disorders that primarily cause progressive spasticity and weakness in the lower limbs due to a length-dependent, ...