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Muscle mass and function after total hip arthroplasty
(2009-04-17)
muscles recovered fully. There was still a reduction in CSA for m. iliopsoas (7.0 %) and hip adductors (8.4 %) and in RD for mm. gluteus maximus (10.1 HU), gluteus medius/minimus (5.6 HU), iliopsoas (3.9 HU) and adductors (2.4 HU). Limp was recovered...
Mechanism of pure glucose-dependent insulinotropic activity of a novel imidazoline compound BL11282
(2008-05-01)
potentiation of insulin release by this peptide. The latter effect points to the importance of GLP-1 stimulated signal-transduction pathways for the insulinotropic activity of BL11282. Our results support the involvement of the cAMP-GEFII·Rim2 pathway in BL...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in ...
Immunological studies on anca-associated vasculitis with special reference to T cell activation
(2009-10-16)
This thesis focuses on the role of T cells in ANCA-associated vasculitis. We initially investigated activation markers on T cells in patients with Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and renal ...
Mechanism of pathological angiogenesis in adipose tissue and tumor
(2009-09-18)
and further investigation of mechanism of angiogenesis in adipose tissue metabolism and cancer development. Multiple factors spatiotemporally regulate adipogenesis and angiogenesis. In a transgenic mouse model described in the first constituent paper, FOXC2...
A new technique to assess dermal absorption of chemical vapor in vitro by thermogravimetric analysis (TGA)
(2008-11-28)
vapor (from water, 2-propanol, methanol and toluene). When no chemical vapor was present the weight of the skin was constant and upon addition of chemical vapor the weight of the skin increased until an equilibrium with the surrounding air was reached...
Genetic and functional analyses of diabetic nephropathy with focus on chromosome 3q
(2010-05-14)
the se-quence for SP1 binding site and subsequently caused the reduction of ADIPOQ promoter activity. The MCF2L2 gene is located in chromosome 3q27.1. A non-synonymous SNP rs7639705 (Leu359Ile) was associated with DN in females. This polymorphism together...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
occurrence of psychoactive plant use in Sweden. Studies were done in attempt to elucidate the metabolic pattern of α- and b-asarone in humans. Cis(b)-2,4,5-trimethoxycinnamic acid was regarded to be the most abundant metabolite, evidence of a hydroxylated...
Peripheral venous catheters : quality of care assessment
(2009-12-31)
About half of the patients admitted to hospitals receive intravenous
therapy through peripheral venous catheters (PVCs). Unfortunately, the
use of PVCs is associated with the risk of complications that may lead to
increased ...
Understanding structure and function of membrane protein transporters
(2008-11-28)
explain why the protein has been difficult to reconstitute into liposomes. Functional studies of CorA from Thermotoga maritima demonstrated that the substrate may be Co2+, and thus Mg2+ may not be the primary substrate of all CorA proteins as previously...