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Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
The flora of the world contains many plants and fungi with stimulant, hallucinogenic and narcotic effects. For centuries, many of these have been used in initiation rites, physical and spiritual healing and rites of ...
DNA repair by HDR in experimental tumorigenesis
(2008-05-15)
The aim of this thesis was to further understand how defects in the homology-directed repair (HDR) pathway affect tumor formation and development. To study proteins involved in HDR is challenging since most of its members ...
Prevention of mother-to-child transmission of HIV-1 using antiretroviral drugs in Dar Es Salaam, Tanzania
(2009-08-21)
for their efficacy to prevent MTCT of HIV in HIV-1-infected pregnant women in Uganda, Tanzania, and South Africa (the Petra trial). In group A treatment was given antepartum for 2 weeks, intrapartum and postpartum for 7 days to mother and infant. In group B...
Epidemiological and recovery facilitating studies of an urban population of stroke patients in Iran
(2010-05-28)
Introduction: Approximately 15 million people have a stroke annually in the world, of whom one third will die within one year and one third will suffer permanent disability. Over 85% of these deaths happen in people living ...
Studies of cannabinoid receptor 1 in mantle cell lymphoma
(2008-11-21)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects
older individuals and has a male predominance. MCL has one of the worst
prognoses among lymphomas and currently there is a search for a curative
therapy. ...
Intramuscular or periosteal acupuncture for patients with chronic musculoskeletal pain in the neck and low back : effects on pain, physical and psychological functioning
(2008-10-23)
Background: Periosteal acupuncture has shown promising results in the
clinic. No studies of effects in patients with chronic pain in the neck
and low back are today available.
Aims: The main purpose was to compare ...
Sickness absence, disability pension, and permanent medical impairment after a car crash
(2017-12-15)
of the cervical spine (ages 16-44; OR: 6.32; CI: 4.42-9.05. Ages 45-64; OR: 17.32; CI: 9.85-30.48). Among the younger (16-44 years), injuries to the lower extremities was the injury type with the second highest OR: 5.64; CI: 4.08-7.81, while among 45-64 year olds...
Brain volume reduction over four decades in multiple sclerosis
(2010-05-07)
at baseline in 1995-1996 and evaluated by MRI over a mean period of 9.25 years (range 7.3-10 years) from 1995-2005. Serial brain atrophy measurements (1D and 2D) were analyzed by one radiologist on a routine PACS workstation, and these results were compared...
Development of novel DNA vaccine and immunotherapeutic approaches
(2009-08-06)
Many potential DNA vaccination and immunotherapeutic strategies has been explored in both animal models and human settings in recent years. However, the failure of efficient and safe method development suggests that it is ...
Characterization of dopamine D1 receptor agonists in vivo : implications for the treatment of schizophrenia and Parkinson's disease
(2008-05-14)
Dopamine is fundamental in human behavior for movement, cognition and
reward. A dysfunctional dopamine system is implicated in several
neurological and psychiatric disorders such as Parkinson s disease and
schizophrenia. ...