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Assessment of HIF-1alpha function and identification of a novel degradation mechanism
(2009-05-22)
proline residues (Pro402 and/or Pro563 within mouse HIF-1alpha), targeting HIF-1alpha for degradation. Initially, it was suggested that mutagenesis of these prolines to alanine residues that cannot be hydroxylated generates a constitutively stabilized form...
Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
The applicability of patient-reported outcomes in primary care : monitoring of patients with asthma or chronic obstructive pulmonary disease
(2009-08-28)
questionnaires detected improvement or deterioration of patients at the group level (paper I). Overall correlations between the criterion measure SGRQ and CCQ were strong for all patients with clinical COPD (0.84). These correlations between CCQ and SGRQ were...
Women who do not attend parental education classes during pregnancy or after birth
(2008-08-15)
, and 4,600 women were eligible for the study according to the Medical Birth Register. The number of responders to the first questionnaire was 3,061, to the second 2,762, to the third 2,563 and to the fourth 1,721. The representativeness of the sample...
Teleost retina : a model to study neurogenesis and angiogenesis
(2009-03-09)
Teleost models, zebrafish and medaka have become popular models to study
various aspects of developmental biology and genetics. The rapid
embryonic development, transparent embryos and the availability of many
mutants ...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
was recorded. The width of the upper dental arch had increased significantly more (p<0.01) in the OSAS children than in the controls, and the lateral cross-bite had spontanously resolved in two patients. Furthermore, changes towards a more normal dentofacial...
Methods for measurement of vocal fold vibration and viscoelasticity
(2009-05-08)
of the lip. The elasticity data showed no differences between the vocal folds, lips or cheeks. The hand data showed significant higher stiffness as compared to the other three measured tissues (p<0.001). The coefficient of variation was about 35% for all...
Epidemiological and recovery facilitating studies of an urban population of stroke patients in Iran
(2010-05-28)
Introduction: Approximately 15 million people have a stroke annually in the world, of whom one third will die within one year and one third will suffer permanent disability. Over 85% of these deaths happen in people living ...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
The flora of the world contains many plants and fungi with stimulant, hallucinogenic and narcotic effects. For centuries, many of these have been used in initiation rites, physical and spiritual healing and rites of ...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
(n=42 814) were analyzed to assess the association of statin therapy at discharge with one year survival. After multivariable adjustment, statin at discharge was associated with a 37% reduction in one year mortality (HR 0.63, 95% CI 0.58-0.68, p<0...