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Aprotinin for reduction of bleeding and transfusions in patients on clopidogrel undergoing urgent coronary surgery
(2009-05-08)
percentile) adenosinediphosphate mediated platelet aggregation before and after aprotinin, was 84% (76/91) and 94% (86/97, p<0.01). Clopidogrel non-responders with >90% aggregation (n=4) had a median aggregation of 94.5% (91.5/97.5) versus 82% (73/87, p<0...
Isoforms of mammalian glutaredoxin 2
(2009-05-05)
Iron-sulfur proteins are characterized by the presence of iron-sulfur clusters containing sulfide linked iron centers in variable oxidation states. Glutaredoxins (Grx) are, among other redoxins, increasingly recognized to ...
Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The ...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
(n=42 814) were analyzed to assess the association of statin therapy at discharge with one year survival. After multivariable adjustment, statin at discharge was associated with a 37% reduction in one year mortality (HR 0.63, 95% CI 0.58-0.68, p<0...
Factors associated with lung function impairment in children and adults with obstructive lung disease
(2008-05-14)
Obstructive lung diseases are a group of diseases in which there is a limitation in the flow of air into or out of the lungs. Two common such diseases are asthma, which is found in both children and adults, and chronic ...
Paroxysmal atrial fibrillation : prognostic implications
(2008-08-29)
This thesis is based on data from the Stockholm Cohort on Atrial
Fibrillation (SCAF). This cohort consists of all 2912 patients with
atrial fibrillation or flutter who were treated as in or outpatients at
South Hospital ...
Epidemiology and care of epilepsy in Vietnam
(2010-05-12)
of active epilepsy were thus identified. Age-adjusted incidence was 44.8/100,000 (95%CI 30.6-59.0), higher in those under 16 years, among people with lower education, and with lower income. Age-adjusted prevalence was 4.4 per 1,000 (95%CI 3.8-5.0), higher...
Study of pruritus in psoriasis vulgaris : role of tachykinins
(2009-01-23)
Pruritus has not been considered as the most important symptom of
psoriasis. In the present thesis various methodologies have been used to
investigate this symptom in psoriasis.
The focus groups created a proper ...
Characterization of dopamine D1 receptor agonists in vivo : implications for the treatment of schizophrenia and Parkinson's disease
(2008-05-14)
Dopamine is fundamental in human behavior for movement, cognition and
reward. A dysfunctional dopamine system is implicated in several
neurological and psychiatric disorders such as Parkinson s disease and
schizophrenia. ...
Screening for intimate partner violence in healthcare in Kano, Nigeria : barriers and challenges for healthcare professionals
(2010-05-05)
Background: Though there has been increased advocacy for screening for Intimate
partner violence (IPV) in healthcare over the past decades, data from
developed country context suggest that only one in ten healthcare
providers ...