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Efficacy of artemisinin based combination therapy and effectiveness of rapid diagnostic test for management of patients with plasmodium falciparum malaria in Zanzibar
(2009-05-19)
. Some 1887 patients were enrolled between February and August 2005. Follow-up was 14 days. ACT was to be prescribed to patients diagnosed with malaria in both groups.
Results: Study I. PCR adjusted cure rates by day 42 were 188/206 (91%) for ASAQ...
Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The ...
Drug treatment in children with focus on off-label drug use
(2010-08-06)
There is a lack of paediatric documentation concerning efficacy and
safety of many drugs, which contribute to drug use outside the terms of the product license (off-label). In the present thesis, four studies (I-IV), using ...
Intimate partner violence against women : foundation for prevention and for an educational programme for new couples in an Iranian city
(2009-05-04)
Understanding how community members conceive the occurrence and
prevention of intimate partner violence against women (IPVAW) can help
set the stage for contextrelevant and sustainable preventive
interventions, including ...
Genetic content of clinical pneumococcal isolates and its relation to disease outcome
(2009-09-30)
carriage or invasiveness. No obvious candidate was found. ARs 6 and 34 were found in most of the invasive isolates and were absent in most of the isolates of low invasive disease potential and were tested for invasiveness in a mouse model of infection. We...
Pharmacological targeting of p53 pathway alterations in tumors
(2010-05-27)
. In the other half of human tumors, p53 is not functional due to extensive degradation by MDM2 or HPVE6/E6AP. Inactivation of p53 is essential for tumor survival, therefore the strategy aimed at restoring its functions is a promising approach for cancer...
Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives
(2009-11-06)
This thesis will mainly focus on the chemistry of nitrogen containing heterocyclic compounds, particularly pyrazole and benzotriazine and related ring systems to these compounds. The first part includes a short introduction ...
Study of pruritus in psoriasis vulgaris : role of tachykinins
(2009-01-23)
Pruritus has not been considered as the most important symptom of
psoriasis. In the present thesis various methodologies have been used to
investigate this symptom in psoriasis.
The focus groups created a proper ...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in ...
New apheresis techniques in transplantation
(2008-11-21)
The shortage of organs for transplantation is a global problem and therefore it is of outmost importance to increase the number of donations and improve long term graft survival. As an effort to increase kidney donations, ...