Search
Now showing items 1-10 of 233
Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
Epigenic regulation and posttranslational modification of human cytochrome P450s : focus on CYP2W1, CYP1A2 and CYP2C18
(2008-11-21)
The cytochrome P450 superfamily represents a very important group of
enzymes that are responsible for the metabolism of drugs as well as of
endogenous compounds. Many P450s are genetically polymorphic causing
important ...
CYP2C-dependent drug metabolism in vivo : influence of genetics and drug interactions
(2010-11-24)
Cytochrome P450 enzymes (CYPs) are responsible for the metabolism of the majority of therapeutic drugs. This thesis focuses on one of the CYP subfamilies, CYP2C, especially CYP2C9 and CYP2C19, which are responsible for the metabolism of 15– 20...
Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(2010-02-05)
Background: The brain atrophy in individual Alzheimer's disease (AD) patients includes not only specific atrophy from AD pathology, but also atrophy induced by normal aging and cerebral vascular diseases. Although medial ...
Development of cannabinoid subtype-1 (CB1) receptor ligands for PET
(2008-05-23)
Introduction: Abnormalities in brain cannabinoid subtype-1 (CB1) receptor
concentrations and/or signaling pathways may be involved in a variety of
psychiatric and neurodegenerative disorders. There is a strong need ...
Mechanism of pathological angiogenesis in adipose tissue and tumor
(2009-09-18)
and further investigation of mechanism of angiogenesis in adipose tissue metabolism and cancer development. Multiple factors spatiotemporally regulate adipogenesis and angiogenesis. In a transgenic mouse model described in the first constituent paper, FOXC2...
Cardiovascular disease prevention after spinal cord injury : a new challenge
(2010-05-07)
Spinal cord injury (SCI) typically leads to permanent infralesional motor
and sensory functional losses, pathophysiological aberrations in most
organ systems and a lasting vulnerability for a variety of complicating
conditions. ...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in ...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
occurrence of psychoactive plant use in Sweden. Studies were done in attempt to elucidate the metabolic pattern of α- and b-asarone in humans. Cis(b)-2,4,5-trimethoxycinnamic acid was regarded to be the most abundant metabolite, evidence of a hydroxylated...
The Rarebit fovea test : a new measure of visual function
(2008-04-23)
Visual acuity (VA) measurement by the use of letter charts is the most
frequently used method for testing foveal function. However, since a
decimal visual acuity of 1.0, often used as limit for normality, can be
achieved ...