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Risk management : the role of clinical factors in violent behaviour
(2009-12-25)
Background: The relationship between clinical factors and reoffending in
psychiatric and correctional populations is unclear, with a lot of
contradictory results and some clinical areas lacking in research. The
overall ...
Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in ...
Role of genes and environment for the development of rheumatoid arthritis : results from the Swedish EIRA study
(2009-01-09)
-environment interaction between HLA-DRB1 SE alleles and smoking; 2. Gene-gene interaction between HLA-DRB1 SE and R620W PTPN22 alleles; 3. Interaction between alcohol consumption, smoking and HLA-DRB1 SE alleles; and 4. Dose dependency between smoking and risk...
Dissection of HIV-1 Env-specific B cell responses in non-human primates
(2010-04-27)
between Env immunogens and CD4-expressing cells would negatively affect the elicitation of Envspecific immune responses, CD4 binding-competent and CD4 binding-defective trimers were constructed and inoculated into non-human primates. No difference...
Heritability and sex differences in experimental neuropathic pain with special emphasis on the role of the major histocompatibility complex
(2008-11-21)
Neuropathic pain caused by injury to the nervous system is a difficult clinical problem and a large proportion of patients experience no or only partial relief from existing treatments. Pain sensitivity and the development ...
Studies on leukotriene B4 and alarmins in inflammatory responses
(2010-01-29)
Leukotriene B4 (LTB4) is a potent proinflammatory lipid mediator that is involved in host defense and inflammatory diseases, such as atherosclerosis. LL-37 and heparin binding protein (HBP) are cationic antimicrobial polypeptides, which belong...
Immunological studies on anca-associated vasculitis with special reference to T cell activation
(2009-10-16)
This thesis focuses on the role of T cells in ANCA-associated vasculitis. We initially investigated activation markers on T cells in patients with Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and renal ...
Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(2010-02-05)
that reflect MTA. In the MRI study (Papers 3&4), 544 healthy non-demented subjects (aged 60-97 years) were recruited from the Swedish National study of Aging and Care in Kungsholmen (SNAC-K). Hippocampal formation and entorhinal cortex were manually delineated...
Nurses in paediatric care : competence, professional identity and research utilization
(2010-04-08)
Paediatric health care is becoming highly specialized and there is a need of nurses with specialist knowledge in the field. A large turnover of personnel and shortage of specially trained paediatric nurses have resulted ...