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Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
-cell interactions of committed ectodermal cells. We also showed that expression of the Wnt PCP signalling gene Vangl2 (Van gogh-like 2) was increased. Wnt7a´s influence on neuronal differentiation was studied by investigation of β-tubulin III expression, a marker...
Teleost retina : a model to study neurogenesis and angiogenesis
(2009-03-09)
Teleost models, zebrafish and medaka have become popular models to study
various aspects of developmental biology and genetics. The rapid
embryonic development, transparent embryos and the availability of many
mutants ...
Alternative splicing of interleukin-7
(2009-04-03)
to function as either agonists or as antagonists of the wildtype cytokine. Interleukin-7 (IL-7) plays a non-redundant role in early stages of normal B and T-cell development; IL-7-receptor signaling is required for the maintenance of T-cell homeostasis...
Body and soul : studies on health and psychosomatic complaints among adolescents in Sweden
(2008-10-07)
Objective: The aim of this thesis is to describe the health of the
adolescents with special emphasis on psychosomatic complaints.
Method: Both quantitative and qualitative methods were used to get a
insight into ...
Structural enzymology of dormancy related proteins from Mycobacterium tuberculosis
(2009-01-09)
Mycobacterium tuberculosis, the causative agent of tuberculosis, is one of the most lethal infectious agents affecting humans. The World Health Organisation estimates that about one-third of the world s population is ...
Storage and transfusion of platelets : in vitro and in vivo studies in healthy volunteers and in allogeneic hemapoetic progenitor cell transplant recipents
(2009-03-13)
Early studies in the 1960´s showed that platelet (PLT) transfusions
significantly reduced the incidence of fatal hemorrhages. Together with
the advances in the hematology and transplantation field, easily
accessible ...
Cancer vaccine strategies and studies of human thioredoxin reductase splice variants
(2010-05-28)
Cancer involves abnormal, uncontrolled proliferation of cells, and evasion from the immune system. Immune evasion can be caused by defects in one or more of the components of the major histocompatibility complex class I ...
Isoforms of mammalian glutaredoxin 2
(2009-05-05)
Iron-sulfur proteins are characterized by the presence of iron-sulfur clusters containing sulfide linked iron centers in variable oxidation states. Glutaredoxins (Grx) are, among other redoxins, increasingly recognized to ...
Studies of cannabinoid receptor 1 in mantle cell lymphoma
(2008-11-21)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects
older individuals and has a male predominance. MCL has one of the worst
prognoses among lymphomas and currently there is a search for a curative
therapy. ...
Lactobacillus based oro-mucosal therapies against rotavirus
(2008-05-09)
Rotavirus is the most important agent for severe infantile diarrhea, responsible for over 2 million diarrhea episodes and 600,000 deaths annually, mainly in the developing countries. Introduction of successful vaccine ...