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Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
Prevention and intervention therapies in auditory trauma
(2009-01-16)
Hearing impairment is one of the most common health conditions in
developed countries. It is estimated that approximately 70 million people
worldwide are deaf. For patients with a severe to profound hearing loss a
cochlear ...
Autoantibodies in congenital heart block
(2009-11-20)
of the postnatal maternal Ro52-, p200-, Ro60- and La antibody levels in infants during their first year. Further, we aimed to identify factors other than autoantibodies influencing the fetal outcome in Ro52 positive pregnancy using experimental models...
Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The ...
Prevention of mother-to-child transmission of HIV-1 using antiretroviral drugs in Dar Es Salaam, Tanzania
(2009-08-21)
, respectively and the RR for HIV infection or death compared to placebo were 0.39, 0.64 and 0.97, respectively. After 18 months of follow up the transmission rates were 14.9% (95%CI 9.4-22.8), 18.1% (12.1-26.2), 20.0% (12.9-30.1) and 22.2% (15.9-30.2) for groups...
Dissection of HIV-1 Env-specific B cell responses in non-human primates
(2010-04-27)
between Env immunogens and CD4-expressing cells would negatively affect the elicitation of Envspecific immune responses, CD4 binding-competent and CD4 binding-defective trimers were constructed and inoculated into non-human primates. No difference...
Development of cannabinoid subtype-1 (CB1) receptor ligands for PET
(2008-05-23)
Introduction: Abnormalities in brain cannabinoid subtype-1 (CB1) receptor
concentrations and/or signaling pathways may be involved in a variety of
psychiatric and neurodegenerative disorders. There is a strong need ...
The role of CYP3A4/5 in alprazolam metabolism
(2010-05-14)
Cytochrome P450 3A (CYP3A) enzyme family is involved in the metabolism of about 50 % of all drugs in clinical use. Among CYP3A, CYP3A4 and CYP3A5 are the major enzymes in adults; however CYP3A5 is polymorphic and primarily expressed in black...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide ...
Applications of nanotechnology in neuroscience : functionalized superparamagnetic nanoparticles as contrast enhancers in experimental magnetic resonance imaging
(2010-04-08)
Magnetic resonance imaging (MRI) is a noninvasive imaging technique that
helps clinicians not only to diagnose but also to plan the treatment of
invasive surgery and actually treat medical conditions. Superparamagnetic
iron ...