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Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
-cell interactions of committed ectodermal cells. We also showed that expression of the Wnt PCP signalling gene Vangl2 (Van gogh-like 2) was increased. Wnt7a´s influence on neuronal differentiation was studied by investigation of β-tubulin III expression, a marker...
Sexual life after childbirth and aspects of midwives’ counselling at the postnatal check-up
(2009-02-27)
The overall aim of this thesis was to explore and describe how sexual
life after childbirth is communicated, addressed and reflected upon among
new mothers, fathers and midwives and the impact of leaving first and
minor ...
Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis
(2008-10-03)
Dengue fever (DF) is the most common global viral mosquito-borne infection, with 100 million estimated cases annually in tropical and subtropical areas. The dengue viruses (genus Flavivirus, Flaviviridae) occur in 4 serotypes ...
Alternative splicing of interleukin-7
(2009-04-03)
to function as either agonists or as antagonists of the wildtype cytokine. Interleukin-7 (IL-7) plays a non-redundant role in early stages of normal B and T-cell development; IL-7-receptor signaling is required for the maintenance of T-cell homeostasis...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide ...
Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives
(2009-11-06)
This thesis will mainly focus on the chemistry of nitrogen containing heterocyclic compounds, particularly pyrazole and benzotriazine and related ring systems to these compounds. The first part includes a short introduction ...
Chest wall sarcomas
(2010-03-05)
Aim: To evaluate initial symptoms and clinical features, diagnosis and delay
in osteosarcoma (OS), Ewing sarcoma (EWS) and chest wall chondrosarcoma
(CS). To assess treatment and identify prognostic factors in chest ...
Determinants of long term course in bipolar disorder
(2010-05-14)
Introduction: Bipolar disorder (BP) is a common and severe psychiatric
illness with a high variability. An early treatment is often crucial for
a good prognosis, but it is difficult for clinicians to define high ...
CD8alpha/alpha+ T-cells and immune memory
(2009-04-29)
TB vaccination and after Mtb infection was further analyzed in Paper IV. CD8αα+ T-cells underwent similar phenotypical changes as observed in the CD4+ and CD8αβ+ T-cell compartments, in vaccinated but not in non-vaccinated animals: loss of IL-7Rα...