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Epidemiologic and genetic studies of paramyxoviruses
(2008-08-21)
virus (RSV), influenza A virus and parainfluenza virus hMPV was the fourth most common respiratory virus with a detection rate of 2,9% (n=143/4,989) in nasopharyngeal samples. genotype A dominated over genotype B. Approximately 2,6% (n=68/2,579) of the h...
Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
The mammalian central nervous system (CNS) consists of the brain and the spinal cord. The entire CNS is derived from the walls of a fluid-filled neural tube that is formed at an early stage of embryonic development. The ...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide ...
Studies of cannabinoid receptor 1 in mantle cell lymphoma
(2008-11-21)
Mantle cell lymphoma (MCL) is a malignant B-cell lymphoma that affects
older individuals and has a male predominance. MCL has one of the worst
prognoses among lymphomas and currently there is a search for a curative
therapy. ...
Tobacco smoking, high body mass index and the outcome after surgery : the role of intervention
(2008-11-07)
The negative effects of smoking and obesity on public health are
well-known. Despite this knowledge, the smoking-attributable morbidity
and mortality is estimated to rise rapidly in the forthcoming years, and
obesity ...
Molecular epidemiology of tuberculosis
(2009-05-07)
Tuberculosis (TB) is a global epidemic, with one third of the world's population infected, at least 9 million new active cases per year and about 2 million deaths per year. Without adequate chemotherapy treatment TB may be a mortal disease...
Asthma treatment in primary care : studies of variability and health economic aspects
(2009-05-15)
Background: Most asthma patients in Sweden are treated in primary care, but little is known about economic aspects of asthma treatment in that setting and about the regional variation in the use of antiasthmatics drugs and ...
Storage and transfusion of platelets : in vitro and in vivo studies in healthy volunteers and in allogeneic hemapoetic progenitor cell transplant recipents
(2009-03-13)
Early studies in the 1960´s showed that platelet (PLT) transfusions
significantly reduced the incidence of fatal hemorrhages. Together with
the advances in the hematology and transplantation field, easily
accessible ...
Prognostic molecular markers of childhood leukemia
(2010-05-21)
and Oncology (NOPHO), we investigated the frequency and clinical implications of the genetic aberration dic(9;20)(p13.2;q11.2), which easily escapes detection by chromosome banding analysis alone. We obtained material and performed interphase FISH on more than...