Search
Now showing items 1-10 of 764
CD8alpha/alpha+ T-cells and immune memory
(2009-04-29)
A better understanding of T-cell memory formation is crucial for rationale vaccine design and the identification of correlates of immune protection. The CD8αα homodimer expressed on CD8+ T-cells is not anymore considered to represent a TCR co...
Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis
(2008-10-03)
and by dengue IgM ELISA. Only samples collected until day 5 post onset were found positive by PCR: in 73% (35/48) of the samples, dengue RNA of serotypes 1, 2 or 3 was detected. The number of genomes/ml varied between 103 and 108, with a gradual decline over...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
for the presence of mescaline. No samples were positive for mescaline, but the method was validated using a clinical sample from a German intoxication case. Urine samples (n=103) from patients admitted to emergency departments all over Sweden were investigated...
Teleost retina : a model to study neurogenesis and angiogenesis
(2009-03-09)
Teleost models, zebrafish and medaka have become popular models to study
various aspects of developmental biology and genetics. The rapid
embryonic development, transparent embryos and the availability of many
mutants ...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
blood count, in particular neutrophils and monocytes, as well as an enhanced IL-8 and soluble ESelectin level. Assisted delivery, associated with the highest degree of fetal stress in addition has an increased Interferon-gamma level. The direct...
Application of metalation reactions for synthesis of sulfur/selenium-containing heterocyclic compounds
(2009-09-25)
This thesis deals mainly with the synthesis of various sulfur/selenium-containing heterocyclic compounds, many of which include structural features present in several biologically active molecules, with particular emphasis ...
Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives
(2009-11-06)
This thesis will mainly focus on the chemistry of nitrogen containing heterocyclic compounds, particularly pyrazole and benzotriazine and related ring systems to these compounds. The first part includes a short introduction ...
Tobacco smoking, high body mass index and the outcome after surgery : the role of intervention
(2008-11-07)
The negative effects of smoking and obesity on public health are
well-known. Despite this knowledge, the smoking-attributable morbidity
and mortality is estimated to rise rapidly in the forthcoming years, and
obesity ...
Molecular characterization of Mycobacterium tuberculosis complex from Kampala, Uganda
(2008-11-27)
Uganda is one of the countries with the highest burden of tuberculosis (TB) in Sub-Saharan Africa, ranked 16th among the 22 high-burden countries in the world. Poor peri-urban areas of developing countries with inadequate ...
Cardiovascular disease prevention after spinal cord injury : a new challenge
(2010-05-07)
Spinal cord injury (SCI) typically leads to permanent infralesional motor
and sensory functional losses, pathophysiological aberrations in most
organ systems and a lasting vulnerability for a variety of complicating
conditions. ...