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Brain MRI and CT morphology in healthy aging and Alzheimer's disease
(2010-02-05)
) together with CSF biomarkers is suggested to be the most important diagnostic markers for AD, it may not be specific. The current method of choice to measure MTA has been volumetric measurement based on 3D magnetic resonance imaging (MRI...
Statistical methods for biomarker discovery in proteomics
(2008-08-15)
Surface-Enhanced Laser Desorption and Ionization (SELDI) is a promising proteomic technique for discovering biomarkers. However, the pre-processing of the raw data is still problematic. Integrating transcriptomic and ...
Neural correlates of individual differences in personality and intelligence : studies using an isochronous timing task and voxel based morphometry
(2009-01-14)
It is easy to imagine that humans have always noticed the differences
between themselves and others and perhaps even speculated about the
origins of these differences. The study of individual differences as a
formal ...
Clinical investigations of fixation stability and reading eye movements
(2009-04-24)
such injury; 3) evaluate if the Tobii system could be used to evaluate reading performance despite its relatively low resolution and sampling frequency; and 4) evaluate if patients with neovascular AMD, treated with Lucentis, gain a better reading ability...
Tissue biomarkers in prostate cancer
(2009-09-25)
Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely ...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
3 times higher compared to C-section indicating fetal peptide release. Neutrophils from cord blood after normal delivery contain 10 times more cytoplasmatic cathelicidin peptide compared to corresponding cells after C-section where a strict granular...
The risk of developing rheumatoid arthritis : epidemiological studies on associations with socioeconomic status, psychosocial work stress and smoking
(2008-09-26)
Rheumatoid arthritis (RA) is a chronic, inflammatory disease. Knowledge
about the contribution of genetics is rapidly increasing, but data on
environmental factors that may cause RA is scarce. The aim of this thesis
was ...
Functional gastrointestinal disorders : co-morbidity and non-somatic aspects
(2008-05-19)
Aims of the thesis: The first aim, (Study I) of this thesis was to
compare co-morbidity of the reported symptoms and its relation to
healthcare seeking behaviour among non-patients who had persistent
functional ...
Brain volume reduction over four decades in multiple sclerosis
(2010-05-07)
at baseline in 1995-1996 and evaluated by MRI over a mean period of 9.25 years (range 7.3-10 years) from 1995-2005. Serial brain atrophy measurements (1D and 2D) were analyzed by one radiologist on a routine PACS workstation, and these results were compared...
Peripheral venous catheters : quality of care assessment
(2009-12-31)
About half of the patients admitted to hospitals receive intravenous
therapy through peripheral venous catheters (PVCs). Unfortunately, the
use of PVCs is associated with the risk of complications that may lead to
increased ...