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Cataract induced by UVR-B 300nm : characterization and genetic modulation of the lens sensitivity to oxidative stress
(2008-03-28)
Cataract is defined as an opacification of the lens resulting in visual
impairment. Worldwide, it is the number one cause of blindness and there
are currently no strategies to prevent the onset of the disease. Cataract
surgery ...
Psychological health and life situation in spouses of stroke patients
(2007-05-25)
About 30,000 people in Sweden are affected by stroke each year. The
effect on physical functioning, and also consequences such as depression
and aphasia, are likely to affect not only the life of the patient, but
also the ...
Menstrual status and long-term cardiovascular effects of intense exercise in top elite athlete women
(2008-03-28)
Although physical exercise is generally beneficial for health, female athletes run an elevated risk of developing chronic energy deficiency, with ensuing severe consequences such as reproductive dysfunction, bone ...
Autocrine and paracrine regulation of Leydig cell survival in the postnatal testis
(2007-09-07)
The primary function of testicular Leydig cells is the production of androgens that promote sexual differentiation in the fetus, secondary sexual maturation at the. time of puberty, and spermatogenesis in the adult. ...
Human serum transferrin glycosylation pattern : population differences, analytical methodology and application as a biomarker for testing of alcohol abuse and CDG
(2007-11-16)
Alcohol use and abuse is a major social and economic problem in many
societies. Carbohydrate-deficient transferrin (CDT) is a widely used and
highly specific biochemical alcohol marker of prolonged alcohol abuse.
Increased ...
Effects pf hypoxia and antiepileptic drugs of electrophysiological properties of CA1 neurons in hippocampus
(2007-05-25)
This thesis is based on three experimental studies (I-III) of CA1 hippocampal neurons in rat brain slices, where the electrophysiological properties are examined with patch clamp technique under hypoxic conditions and ...
Placebo, alcohol and flumazenil provocations : subjective and objective registrations in psychopharmacological experiments
(2007-01-12)
Abuse and dependency of alcohol or drugs is a major problem today, with
severe implications for society as well as for the individual. Treatment
is often characterised by hard work and the road to recovery is (among
other ...
Pulmonary tuberculosis and Pneumocystis jiroveci pneumonia in HIV-infected patients in Ethiopia
(2007-02-12)
The objective of this study initially was to determine the prevalence of
culture-verified pulmonary tuberculosis in TB suspects and investigate
the impact of human immunodeficiency virus (HIV) infection on the
prevalence, ...
Exposure to skin irritants : validation of questions and epidemiological aspects
(2008-03-14)
Hand eczema is common, and is the most frequent occupational skin disease. Exposure to skin irritants contributes to hand eczema. Common skin irritants are water, detergents, chemicals and foodstuffs. The aim of this thesis ...
Autocrine/paracrine interactions moendocrine pancreasdulating hormone release in the endocrine pancreas
(2007-11-07)
Human islet transplantation is emerging as an alternative to pancreas transplantation or insulin therapy in the treatment of type I diabetes. It has been possible to achieve euglycemia by transplanting isolated human islets ...