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Analysis of neuropathic pain after spinal cord injury
(2008-01-18)
Longstanding neuropathic pain is a challenge in spinal cord injury (SCI) rehabilitation. Once established it is difficult to treat successfully. Neuropathic pain has a negative influence on quality of life and on the outcome ...
Functional genomics studies of PINK1
(2007-10-25)
uptake. Secondly, FABP4, a lipid transport protein, was selectively down regulated following PINK1 knockdown in adipocytes. However, mitochondrial genes were not altered when PINK1 expression was ablated, despite the in vivo association between such genes...
From stem cells to neurons : a BMPy ride
(2007-10-05)
neural specification, BMP4 promotes astrocytic while inhibiting oligodendrocytic cell fates, an activity by BMP4 also seen in NSCs. Furthermore, the differentiation downstream of BMP4 in NSCs is dependent on the cell density, inducing mesenchymal...
Caesarean section on maternal request : personality, fear of childbirth and signs of depression among first-time mothers
(2007-05-15)
Aim: The overall aim of this thesis was to study healthy first-time mothers
requesting and undergoing an elective caesarean section (CS) and to
compare these to healthy first-time mothers planning a vaginal delivery.
The ...
Joint destruction in rheumatoid arthritis : experimental, clinical and epidemiological studies
(2007-11-23)
Background: Rheumatoid arthritis (RA) is a common autoimmune disease
characterized by chronic polyarticular synovial inflammation. Erosive
joint destruction represents a major unsolved complication of RA.
Objectives: ...
Toxicological studies of opiate-related death
(2007-04-25)
This thesis comprises studies on opiate overdose death, and focuses on
evaluation of toxicological characteristics including the possible
influence of abstinence and polydrug use for the fatal outcome.
In order to ...
Studies of immunopathogenic mechanisms and treatment of chronic, inflammatory myopathies, myositis
(2007-10-12)
Polymyosit (PM), dermatomyositis (DM) and sporadic inclusion body
myositis (sIBM) are chronic inflammatory myopathies which are
characterized by muscle weakness, fatigue and extra-muscular involvement.
Mononuclear ...
Menstrual status and long-term cardiovascular effects of intense exercise in top elite athlete women
(2008-03-28)
Although physical exercise is generally beneficial for health, female athletes run an elevated risk of developing chronic energy deficiency, with ensuing severe consequences such as reproductive dysfunction, bone ...
Exposure to skin irritants : validation of questions and epidemiological aspects
(2008-03-14)
Hand eczema is common, and is the most frequent occupational skin disease. Exposure to skin irritants contributes to hand eczema. Common skin irritants are water, detergents, chemicals and foodstuffs. The aim of this thesis ...
Placebo, alcohol and flumazenil provocations : subjective and objective registrations in psychopharmacological experiments
(2007-01-12)
Abuse and dependency of alcohol or drugs is a major problem today, with
severe implications for society as well as for the individual. Treatment
is often characterised by hard work and the road to recovery is (among
other ...