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Studies on natural antisense RNAs and microRNAs
(2007-11-27)
Regulatory RNAs are found in all kingdoms of life and involved in
regulation of gene expression at various steps including RNA splicing,
editing, stability, modification, export, translation and chromatin
remodelling. ...
Molecular dynamics simulations of RNA bulges, loops and base flipping
(2008-01-11)
RNA molecules have several important functions in a cell. They carry the genetic information from DNA to protein, act as catalysts and regulate gene expression. Both DNA and RNA consist of nucleotides, DNA molecules are ...
Alcohol and inflammation : a study of effects of ethanol on endothelial and epithelial cell functions
(2007-10-26)
to become ex-posed to ethanol following ingestion. In this thesis I explored their reactions to ethanol and EtP in the setting of an acute inflammatory reaction, e.g. after challenge with LPS, IL-1, TNFalpha or LTB4 mimicking, for instance, sepsis...
Psychological health and life situation in spouses of stroke patients
(2007-05-25)
About 30,000 people in Sweden are affected by stroke each year. The
effect on physical functioning, and also consequences such as depression
and aphasia, are likely to affect not only the life of the patient, but
also the ...
Ultrasound, ions and combined modalities for increased local tumour cell death in radiation therapy
(2007-05-03)
In this thesis, new approaches to improve tumour therapy for patients with inoperable, radiation- and chemoresistant tumours were in focus. Ultrasound and ionising radiation, especially accelerated ions, are both non-invasive ...
Menstrual status and long-term cardiovascular effects of intense exercise in top elite athlete women
(2008-03-28)
Although physical exercise is generally beneficial for health, female athletes run an elevated risk of developing chronic energy deficiency, with ensuing severe consequences such as reproductive dysfunction, bone ...
Cardiorespiratory fitness and cardiovascular disease risk factors in children and adolescents
(2007-03-09)
Cardiovascular disease (CVD) events occur most frequently during or after the fifth decade of life, however, there is evidence indicating that the precursors of CVD has its origin already in the first or second decade of ...
In vivo imaging of islet cells and islet revascularization
(2007-03-02)
Glucose homeostasis depends on the release of insulin from the pancreatic
beta-cell. Impaired insulin release is a hallmark of diabetes mellitus.
The beta-cells are situated within the endocrine pancreas, the islets ...
Cardiorespiratory fitness and cardiovascular disease risk factors in children and adolescents
(2007-03-09)
Cardiovascular disease (CVD) events occur most frequently during or after the fifth decade of life, however, there is evidence indicating that the precursors of CVD has its origin already in the first or second decade of ...
Placebo, alcohol and flumazenil provocations : subjective and objective registrations in psychopharmacological experiments
(2007-01-12)
Abuse and dependency of alcohol or drugs is a major problem today, with
severe implications for society as well as for the individual. Treatment
is often characterised by hard work and the road to recovery is (among
other ...