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Limitations of maximal oxygen uptake during whole-body exercise
(2007-10-26)
Oxygen uptake increases linearly with increased running speed or rate of
work and finally reaches a maximum beyond which no effort can drive it
further. This phenomenon is referred to as the plateau in oxygen
uptake . ...
Modulation of acetylcholine release by serotonergic 5-HT1A and 5-HT1B receptors : a microdialysis study in the awake rat
(2007-05-25)
extracellular levels of ACh to a maximum of about
350% of the control values, thereafter the ACh concentrations returned to
the normal levels within 80 min. The AUCs calculated for 80 min after the
administration of robalzotan (3 µmol/kg) or donepezil (1 mg...
Tonsillar cancer : incidence, prevalence of HPV and survival
(2008-04-04)
Since human papilloma virus (HPV) in the mid 1980ies was first observed
in squamous cell carcinoma of the head and neck, its role and impact,
especially on oral and oropharyngeal cancer, have attracted extensive
interest. ...
Mother and newborn adaptations after birth : influence of administration of oxytocin and epidural analgesia during labour
(2009-08-31)
Aims: This thesis explores postpartum physiological and psychological adaptations in mothers and newborns in the short-and long-term perspective. The thesis further explores the influence of labour ward interventions, such ...
Cardiorespiratory fitness and cardiovascular disease risk factors in children and adolescents
(2007-03-09)
Cardiovascular disease (CVD) events occur most frequently during or after the fifth decade of life, however, there is evidence indicating that the precursors of CVD has its origin already in the first or second decade of ...
Knowledge acquisition in patients with heart disease
(2007-09-07)
The general aim was to evaluate different aspects of the knowledge
acquisition process in patients with heart disease. Three different
education programs were evaluated.
In Paper I 208 patients with systolic heart failure ...
Healing of tympanic membrane perforations : an experimental study
(2007-05-24)
Most acute tympanic membrane perforations heal spontaneously without any
residual complication, whereas a fraction transforms into a chronic
perforation. The current treatment of a chronic perforation is surgical
repair, ...
Alcohol and inflammation : a study of effects of ethanol on endothelial and epithelial cell functions
(2007-10-26)
to become ex-posed to ethanol following ingestion. In this thesis I explored their reactions to ethanol and EtP in the setting of an acute inflammatory reaction, e.g. after challenge with LPS, IL-1, TNFalpha or LTB4 mimicking, for instance, sepsis...
Transcriptional and post-transcriptional regulation of telomerase reverse transcriptase (hTERT) expression : the role of histone modification and alternative splicing
(2008-01-18)
Telomerase, an RNA-dependent DNA polymerase responsible for telomeric DNA
elongation, is silent in most normal differentiated human cells due to
the tight repression of its catalytic unit, telomerase reverse
transcriptase ...
Chemokines and chemokine receptors during viral infections in man
(2007-11-08)
tissue. Activation of B lymphocytes is accompanied by alternations in chemokine responsiveness that brings together the antigen specific B cells with its cognate CD4 T cell. Several human viral infections have been shown to interfere with chemokine...