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Strategies to increase effectiveness of growth factor receptors-targeted therapy in glioblastoma
(2007-11-14)
Gliomas are the most common glial neoplasms, accounting for nearly 70% of
all primary brain tumours. The progression of low-grade gliomas into more
aggressive tumours is supported by the abnormal function of several
prot ...
Hypnosis monitoring during general anaesthesia : with focus on awareness
(2007-11-09)
An objective measure of the hypnotic component of general anaesthesia
has been sought for decades. The electroencephalogram (EEG) was early recognized as a possible useful
intraoperative monitor when the effects of ...
Blood donors' long-term health : implications for transfusion safety
(2007-11-12)
Continuous attention to transfusion safety through improvement of disease
screening and donor selection has succeeded in reducing the risks of
transfusion transmitted disease to practically immeasurable levels.
Despite ...
International migration and coronary heart disease : epidemiological studies of immigrants in Sweden
(2007-10-05)
In today's globalised world, with considerable international migration,
knowledge about the health of immigrants is becoming increasingly
important. In Sweden, about 13% of the population or over one million
persons are ...
Aphasia in acute stroke
(2007-04-20)
Aphasia is a language impairment due to a brain lesion, usually in the left hemisphere, and is a common symptom in acute stroke. The aims of this thesis were to evaluate aphasia in acute stroke patients, to assess spontaneous ...
Ultrasound, ions and combined modalities for increased local tumour cell death in radiation therapy
(2007-05-03)
In this thesis, new approaches to improve tumour therapy for patients with inoperable, radiation- and chemoresistant tumours were in focus. Ultrasound and ionising radiation, especially accelerated ions, are both non-invasive ...
Analysis of kidney glomerular and microvascular transcriptomes
(2007-09-21)
Kidney glomeruli play a crucial role in the maintenance of body homeostasis. Many diseases attack the kidney function by primarily affecting glomeruli. However, the transcriptome profiles and the function of the glomerulus ...
The impact of airway-irritating exposure and wet work on subjects with allergy or other sensitivity : epidemiology and mechanisms
(2007-09-14)
The prevalence of asthma and allergies is increasing, which means that
the proportion of workers on the labour market with allergy or other
sensitivity also increases. It is as of yet not known to what extent
these ...
Serum proteins in type 1 diabetes
(2007-01-05)
We have previously shown that there are patients with type 1 diabetes T1D
whose sera interfere with cytoplasmic free Ca2+-concentration ([Ca2+]i),
resulting in â-cell apoptosis. In this study the frequency of sera, ...
Studies on the prevalence of reduced salivary flow rate in relation to general health and dental caries, and effect of iron supplementation
(2007-11-23)
-inactive patients. A blood sample was analysed for serum ferritin. In Study III the unstimulated salivary flow rate was tested at 7:30 and 11:30 a.m. in 108 individuals, age 15-46 years. The participants were allocated to one of three groups (very low <0.1 m...