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Passive volume reduction heart surgery using the Acorn CorCap cardiac support device
(2007-09-14)
Heart failure is a growing health problem, affecting an increasing number
of patients with rapidly increasing costs for the health care system. In
spite of recent improvements in pharmacological, non-pharmacological ...
Physical activity in the severely obese : studies on measurement and promotion
(2007-03-26)
Background: The amount and quality of evidence on how to effectively
promote physical activity (PA) is low compared to what is known about the
health effects of regular PA, especially in obese individuals.
Aim : ...
Studies on human sterol 27-hydroxylase with emphasis on its mechanism of regulation and metabolic consequences of a deficient enzyme
(2007-05-11)
Sterol 27-hydroxylase (CYP27A1) is a mitochondrial cytochrome P-450
enzyme present in most animal cells. In hepatocytes, CYP27A1 has an
important role in connection with biosynthesis of bile acids from
cholesterol. In ...
In vitro modelling of tau phosphorylating kinases : emphasis of Cdk5
(2007-11-27)
culture systems were investigated as in vitro
models for tau phosphorylating kinases, with an emphasis on
cyclin-dependent kinase-5 (Cdk5).
In paper I, differentiated SH-SY5Y cell line was investigated as a model
for tau phosphorylation. Sequential...
Autocrine and paracrine regulation of Leydig cell survival in the postnatal testis
(2007-09-07)
The primary function of testicular Leydig cells is the production of androgens that promote sexual differentiation in the fetus, secondary sexual maturation at the. time of puberty, and spermatogenesis in the adult. ...
Economic burden of diabetes on patients and their families in Sudan
(2007-11-27)
childhood was USD 283 per diabetic child, of which 36% was spent on insulin. The direct median cost of diabetes care of type 2 adult diabetes patients was USD 175 per year, which included the cost of drugs and ambulatory care. These costs represent 23% and 9...
Analysis of neuropathic pain after spinal cord injury
(2008-01-18)
Longstanding neuropathic pain is a challenge in spinal cord injury (SCI) rehabilitation. Once established it is difficult to treat successfully. Neuropathic pain has a negative influence on quality of life and on the outcome ...
Role of inflammatory and mitochondria genes in adipose tissue and obesity
(2007-09-28)
arachidonate 5 lipoxygenase activating protein (ALOX5AP) was first implicated in CVD in men. We aimed to investigate its role in obesity in adipose tissue. We found the mRNA expression to be increased in obesity and strongly associate to insulin resistance...
Exposure to skin irritants : validation of questions and epidemiological aspects
(2008-03-14)
Hand eczema is common, and is the most frequent occupational skin disease. Exposure to skin irritants contributes to hand eczema. Common skin irritants are water, detergents, chemicals and foodstuffs. The aim of this thesis ...
Antibiotic resistance and antibiotic consumption with focus on Escherichia coli and Pseudomonas aeruginosa
(2007-05-04)
. coli resistance to ciprofloxacin increased from 0% in 1991 to 11% in 1999 and co-trimoxazole resistance increased in E. coli from 7.5% to 14% during the study period. For E. coli, resistance to ciprofloxacin was higher at the hospital than at the ICUs...