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Family caregivers of relatives with a life-threatening cancer disease
(2007-05-15)
and development in relational functioning during the first year after the patients diagnosis. In a sample of 91 significant others, data was collected on four occasions. Fifty-two percent of significant others reported change in relational functioning during...
Laparoscopic cholecystectomy : patient's experiences and self-reported symptoms the first week after surgery
(2007-11-29)
Very little research has been conducted to identify patients own
perspectives of having gallstone disease and their own experiences of
symptoms the first postoperative week following laparoscopic
cholecystectomy, LC. ...
Perceived allergy and hypersensitivity – especially food hypersensitivity – and the consequences for children, adolescents and their families
(2007-10-26)
Background: Allergy and hypersensitivity are growing health issues with impact on the individual’s physical and psychosocial quality of life, work and social life. This thesis focuses on children and adolescents with ...
Predictors of cognitive decline in memory clinic patients
(2007-05-18)
Background: The major challenge in memory clinics is to predict
development as well as non-development of dementia among the
heterogeneous group of patients with cognitive complaints. Since the
advent of pharmacological ...
Autocrine and paracrine regulation of Leydig cell survival in the postnatal testis
(2007-09-07)
by immature rats Leydig cells., (ii) possible antiapoptotic effects of IGF-I during testicular development and the role played by IGF-1R in this context; (iii) the influence of IGFBP-3 on apoptosis and steroidogenesis in rat Leydig cells in relation...
Effects of endurance exercise on mitochondrial efficiency, uncoupling and lipid oxidation in human skeletal muscle
(2006-12-29)
of uncoupling protein 3 (UCP3), but the functional role of UCP3 in non-coupled respiration is not completely understood. The aim of this thesis was to investigate mitochondrial efficiency (P/0 ratio), mitochondrial fat oxidation, noncoupled respiration (state 4...
Insulin-like growth factor binding protein-3 : structure and function
(2007-11-02)
in the circulation. We have studied posttranslational modification of IGFBP-3, such as proteolysis and glycosylation, and their impact on IGF binding and actions. The IGFBPs have IGF binding sites in the N- and C-terminal domains. Prior to this thesis the binding...
Toxicological studies of opiate-related death
(2007-04-25)
This thesis comprises studies on opiate overdose death, and focuses on
evaluation of toxicological characteristics including the possible
influence of abstinence and polydrug use for the fatal outcome.
In order to ...
Serum proteins in type 1 diabetes
(2007-01-05)
We have previously shown that there are patients with type 1 diabetes T1D
whose sera interfere with cytoplasmic free Ca2+-concentration ([Ca2+]i),
resulting in â-cell apoptosis. In this study the frequency of sera, ...
Involvement of evolutionarily plastic regions in cancer associated CHR3 aberrations
(2007-05-04)
A functional test to identify tumor antagonizing regions on chromosome 3
(chr3), called the Elimination Test, was developed in our group. It is
based on microcell mediated transfer of human chr3 into mouse or human
tumor cells and analysis...