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Regulation of the pro-apoptotic protein Bim by T cell receptor triggering in human T cells
(2006-12-29)
Bim is a significant pro-apoptotic member of Bcl-2 family of proteins; it is proved to be an important regulator of apoptosis: over the years it has been shown to play a pivotal role for the development and maintenance of ...
Caesarean section on maternal request : personality, fear of childbirth and signs of depression among first-time mothers
(2007-05-15)
Aim: The overall aim of this thesis was to study healthy first-time mothers
requesting and undergoing an elective caesarean section (CS) and to
compare these to healthy first-time mothers planning a vaginal delivery.
The ...
Psychological health and life situation in spouses of stroke patients
(2007-05-25)
About 30,000 people in Sweden are affected by stroke each year. The
effect on physical functioning, and also consequences such as depression
and aphasia, are likely to affect not only the life of the patient, but
also the ...
Human serum transferrin glycosylation pattern : population differences, analytical methodology and application as a biomarker for testing of alcohol abuse and CDG
(2007-11-16)
Alcohol use and abuse is a major social and economic problem in many
societies. Carbohydrate-deficient transferrin (CDT) is a widely used and
highly specific biochemical alcohol marker of prolonged alcohol abuse.
Increased ...
Molecular dynamics simulations of RNA bulges, loops and base flipping
(2008-01-11)
RNA molecules have several important functions in a cell. They carry the genetic information from DNA to protein, act as catalysts and regulate gene expression. Both DNA and RNA consist of nucleotides, DNA molecules are ...
Modulation of nuclear receptor function by interacting proteins
(2007-08-21)
Nuclear receptors are a family of transcription factors involved in many
biological processes. They represent key potentials as therapeutic
targets for several clinical conditions such as diabetes, obesity,
cardiovascular ...
Analgetic and algetic effects of adenosine in healthy volunteers and patients with coronary disease
(2007-11-23)
Background: Adenosine is a bimodal neuromodulator with algesic and analgesic effects. The different effects of adenosine are partly due to the route of administration. Low-dose adenosine infusion induces analgesia at the ...
Asthenopia in schoolchildren
(2007-05-11)
movements were recorded before and after treatment of asthenopia, using the IR corneal reflection technique, Orbit Eye trace System. Large variations in reading patterns were found. Despite successful accommodative treatment (p < 0.001), no correlation...
Esophageal cancer surgery : factors influencing survival
(2007-01-19)
The principal aim of this thesis was to address factors that may affect
survival after esophageal cancer surgery. Surgical resection remains the
only established potentially curative treatment for patients with
resectable ...
Ultraviolet radiation cataract development and ascorbate supplementation
(2008-05-15)
Background: Cataract is the major cause of blindness in the world, and
long-term solar ultraviolet radiation (UVR) is a major risk factor. The
pathogenesis of UVRinduced cataract is studied in various animal models
and ...